Codependency and Prefrontal Cortex Functioning: Preliminary Examination of Substance Use Disorder Impacted Family Members.

Background And Objectives: Substance use disorders (SUDs) have negative impacts on an entire family system and each family member may be at risk to develop a "codependency" on their SUD loved-one. Research has demonstrated that SUDs in the family environment associate with altered brain functioning of family members; however, research has not examined specific associations between codependency and brain functioning.

Methods: Prefrontal cortex (PFC) activation of family members (n = 38) was assessed using functional near-infrared spectroscopy as they viewed images of a SUD loved-one (experimental group; n = 26) or of a "target family member" (control group; n = 12).