Pharmacovigilance monitoring and treatment adherence in patients on anti-tubercular drugs.

Background: Tuberculosis (TB) is a chronic infectious disease that involves 6-9 months regimen with different combinations of drugs. Poor adherence can lead to prolonged treatment, higher cost, spurt in new cases and the development of resistance. Directed Observed Therapy (DOTS) are recommended to reinforce adherence for the treatment of TB.

Analysis of lung function and respiratory symptoms in brass/metal industrial workers of Moradabad, Uttar Pradesh, India.

Background: The job demands of some of the industries have been reported to be hazardous to the health and safety of workers. Workplace environmental hazards or occupational hazards are a globally major cause of disability and mortality among the working population. The present study was done to analyze the effect of exposure to metal dust on pulmonary function and respiratory symptoms.

Glutathione -transferase gene polymorphism and asthma: a case-control study in a pediatric population.

To carry out a case-control study of the association of gene polymorphisms in pediatric asthma-related oxidative stress. Asthma patients (n = 250) and age-matched healthy subjects (n = 250) DNA were genotyped for (+/+, +/-, -/+ and -/-) frequencies using multiplex-PCR and plasma oxidative stress markers (examined spectrophotometrically). Asthma patients had significantly more common null-genotype (10.