The use of guided tissue regeneration in endodontic Microsurgery: Setting a threshold.

Aim: We aimed to compare the radiographic outcomes of conventional and regenerative approaches in endodontic microsurgery (EMS) and set a critical defect size for healing in conventional and regenerative therapies.

Methodology: The study evaluated 53 root canal-treated teeth (33 patients) with periapical lesions. Among them, 19 teeth (35.

Randomized controlled trials in neurosurgery.

Randomized controlled trials (RCTs) have become the standard method of evaluating new interventions (whether medical or surgical), and the best evidence used to inform the development of new practice guidelines. When we review the history of medical versus surgical trials, surgical RCTs usually face more challenges and difficulties when conducted. These challenges can be in blinding, recruiting, funding, and even in certain ethical issues.

Inverted stent deployment technique for stent assisted coiling of wide-necked posterior communicating artery aneurysm: Technical report.

Background: Wide-necked aneurysms of the posterior communicating artery associated with a fetal posterior cerebral artery that arises from the neck or dome of the aneurysm is a clinical scenario that poses a challenge to endovascular methods.

Case Description: A patient presented with spontaneous subarachnoid hemorrhage and was found to have a 4 × 3 × 3 mm posterior communicating artery aneurysm. Of note the aneurysm projected superiorly and a fetal posterior communicating artery aneurysm arose from the neck of the aneurysm.

Comparison of Two Drainage Systems on Chronic Subdural Hematoma Recurrence.

Background:  Chronic subdural hematoma (CSDH) is a common type of intracranial hemorrhage, especially among the elderly, with a recurrence rate as high as 33%. Little is known about the best type of drainage system and its relationship with recurrence. In this study, we compare the use of two drainage systems on the recurrence rate of CSDH.

Anterior loop of the mental nerve in Saudi sample in Riyadh, KSA. A cone beam computerized tomography study.

Background: The portion of inferior alveolar nerve (IAN) existent anterior to the mental foramen, before parting the canal, is referred to as the anterior loop (AL) of the IAN. The presence of AL is important when placing the implant interforaminal area of the mandible. These anatomical discrepancies can be assessed by cone-beam CT (CBCT), for evaluating its position and exact location.

Frame-based versus frameless stereotactic brain biopsies: A systematic review and meta-analysis.

Background: Stereotactic brain biopsy techniques have been a focus of rapid technological innovation. The recent advent of frameless stereotaxy has invited the question of whether it can provide the same diagnostic yield as frame-based techniques, without increasing risk of harm to patients. The goal of this meta-analysis was to compare each of these techniques in terms of yield and safety.

Quality of communicating design features for cobalt chromium removable partial dentures in Riyadh, Saudi Arabia.

Purpose: This survey aimed to investigate quality of communicating design features for the construction of cobalt chromium removable partial dentures (RPDs) among dentists in Riyadh, Saudi Arabia.

Materials And Methods: A survey of nine commercial dental laboratories located in Riyadh was carried out. In each visit, master casts for cobalt chromium RPDs and dentists' prescriptions were examined.

The Effect of Oral Health Knowledge, Attitude, and Practice on Periodontal Status among Dental Students.

Objectives:  The primary aim of the current study is to relate oral health knowledge, attitude, and oral hygiene practice with the periodontal condition of both undergraduate and postgraduate dental students.

Materials And Methods:  Data were collected through a combination of self-reported questionnaire and clinical examination. The estimated sample size was 246.

Endoscopic versus open microvascular decompression for trigeminal neuralgia: a systematic review and comparative meta-analysis.

Objective: Microvascular decompression (MVD) is commonly used in the treatment of trigeminal neuralgia (TN) with positive clinical outcomes. Fully endoscopic MVD (E-MVD) has been proposed as an effective minimally invasive alternative, but a comparative review of the two approaches has not been conducted. The authors performed a meta-analysis of studies, comparing patient outcome rates and complications for the open versus the endoscopic technique.

Biopsy Versus Subtotal Versus Gross Total Resection in Patients with Low-Grade Glioma: A Systematic Review and Meta-Analysis.

Background: The role of the extent of surgical resection (EOR) in clinical outcomes for patients with low-grade glioma requires further examination. The goal of the present study was to evaluate the association between variable degrees of EOR and clinical outcomes for patients with low-grade glioma.

Methods: We conducted a systematic review and meta-analysis and searched databases for reports of low-grade glioma EOR.

Prevalence and Predictors of Gastroesophageal Reflux Disease After Laparoscopic Sleeve Gastrectomy.

Background And Aims: Laparoscopic sleeve gastrectomy (LSG) might be associated with a new onset or worsening of gastroesophageal reflux disease (GERD). We aim to evaluate the prevalence of post-LSG GERD symptoms and its predictors.

Methods: We included patients who underwent primary LSG at a university hospital from 2009 to 2015.

Smad2 overexpression induces alveolar bone loss and up regulates TNF-α, and RANKL.

Objective: The aim of the current study was to investigate whether Smad2 overexpression in JE cells induced alveolar bone loss, and to understand the mechanisms regulating the bone loss.

Methods: A mouse line was created that used a cytokeratin 14 (K14) promoter to overexpress Smad2 in the epithelium of the transgenic mice (K14-Smad2). Micro CT radiographs (μCT) were used to assess bone loss, bone volume, and bone density.

Olmsted syndrome with oral involvement, including premature teeth loss.

Introduction: Olmsted syndrome is a rare palmoplantar keratodermal disease that has not previously been reported to have an association with periodontal disease. The aim of this study is to report and document a case of Olmsted syndrome with evidence of severe periodontal disease.

Case Report: A 38-year old Saudi male patient presented to the dental clinic diagnosed previously with Olmsted syndrome.

Smad2 is involved in the apoptosis of murine gingival junctional epithelium associated with inhibition of Bcl-2.

Objective: Gingival junctional epithelium (JE) actively contributes to the homeostasis of the periodontium. Altered activation of TGF-β signalling is implicated in the epithelium from chronic periodontitis. However, little is known about the effects of TGF-β signalling on the JE.