Study on Fabrication and Properties of Polyvinyl Alcohol/Chitosan Nanofibers Created from Aqueous Solution with Acetic Acid and Ethanol by the Electrospinning Method.

The development of nanofibers with incorporated biologically active molecules with a targeted mode of action is a current research trend. Potential materials for the development of such systems include poly(vinyl alcohol) (PVA) and chitosan (CS) nanofibers, which are traditionally fabricated by the electrospinning of aqueous solutions of these polymers with acetic acid. To improve drug integration, ethanol was added to the binary-solvent system.

Evaluation of composition effects on the tissue-adhesive, mechanical and physical properties of physically crosslinked hydrogels based on chitosan and pullulan for wound healing applications.

Tissue adhesion of hydrogels plays an important role in wound healing, which can improve the efficiency of wound treatment, stop bleeding, facilitate tissue growth and wound closure. However, most non-covalent crosslinked hydrogels have weak tissue adhesion and rheological properties. Furthermore, it remains a challenge to synthesize a fully physically crosslinked hydrogel with good rheological properties without compromising its tissue adhesion strength.

Influence of Thermal Treatment and Acetic Acid Concentration on the Electroactive Properties of Chitosan/PVA-Based Micro- and Nanofibers.

This study presents, for the first time, a comprehensive investigation of the influence of pre- and post-fabrication parameters for the electroactive properties of electrospun chitosan/PVA-based micro- and nanofibers. Chitosan/PVA fibers were fabricated using electrospinning, characterized, and tested as electroactive materials. Solutions with different acetic acid contents (50, 60, 70, and 80 %) were used, and the rheological properties of the solutions were analyzed.

Effect of Monomers of 3-Hydroxyhexanoate on Properties of Copolymers Poly(3-Hydroxybutyrate- 3-Hydroxyhexanoate).

The properties of poly(3-hydroxybutyrate--3-hydroxyhexanoate) P(3HB--3HHx) copolymers with different ratios of monomers synthesized by the wild-type strain B-10646 on sugars, and an industrial sample from Kaneka synthesized by the recombinant strain NSDG-ΔfadB1 on soybean oil, were studied in a comparative aspect and in relation to poly(3-hydroxybutyrate) P(3HB). The copolymer samples, regardless of the synthesis conditions or the ratio of monomers, had reduced values of crystallinity degree (50-60%) and weight average molecular weight (415-520 kDa), and increased values of polydispersity (2.8-4.

Chitosan/PVA Nanofibers as Potential Material for the Development of Soft Actuators.

Chitosan/PVA nanofibrous electroresponsive soft actuators were successfully obtained using an electrospinning process, which showed fast speed displacement under an acidic environment. Chitosan/PVA nanofibers were prepared and characterized, and their electroactive response was tested. Chitosan/PVA nanofibers were electrospun from a chitosan/PVA solution at different chitosan contents (2.

Pullulan-Based Hydrogels in Wound Healing and Skin Tissue Engineering Applications: A Review.

Wound healing is a complex process of overlapping phases with the primary aim of the creation of new tissues and restoring their anatomical functions. Wound dressings are fabricated to protect the wound and accelerate the healing process. Biomaterials used to design dressing of wounds could be natural or synthetic as well as the combination of both materials.

ATR-FTIR spectrum analysis of plasma samples for rapid identification of recovered COVID-19 individuals.

The development of fast, cheap and reliable methods to determine seroconversion against infectious agents is of great practical importance. In the context of the COVID-19 pandemic, an important issue is to study the rate of formation of the immune layer in the population of different regions, as well as the study of the formation of post-vaccination immunity in individuals after vaccination. Currently, the main method for this kind of research is enzyme immunoassay (ELISA, enzyme-linked immunosorbent assay).

A Review on Chitosan and Cellulose Hydrogels for Wound Dressings.

Wound management remains a challenging issue around the world, although a lot of wound dressing materials have been produced for the treatment of chronic and acute wounds. Wound healing is a highly dynamic and complex regulatory process that involves four principal integrated phases, including hemostasis, inflammation, proliferation, and remodeling. Chronic non-healing wounds are wounds that heal significantly more slowly, fail to progress to all the phases of the normal wound healing process, and are usually stalled at the inflammatory phase.

Method of manufacturing and staining microplastics for using in the biological experiments.

Nowadays, plastic pollution attracts much attention both from society and scientists. The plastic pollution impact on the environment and human health requires assessment urgently, especially through experimental studies. However, such studies are still scarce because of the lack of standard methods for assessing their effects on living organisms.

Study of the Nanofibers Fabrication Conditions from the Mixture of Poly(vinyl alcohol) and Chitosan by Electrospinning Method.

Nanofiber fabrication is attracting great attention from scientists and technologists due to its applications in many fields of life. In order to design a nanosized polymer-based drug delivery system, we studied the conditions for the fabrication of electrospun nanofibers from poly (vinyl alcohol) (PVA) and chitosan (CS), which are well-known as biocompatible, biodegradable and non-toxic polymers that are widely used in the medical field. Aiming to develop nanofibers that can directly target diseased cells for treatment, such as cancerous cells, the ideal choice would be a system that contains the highest CS content as well as high quality fibers.

High-Porosity Polymer Composite for Removing Oil Spills in Cold Regions.

In this work, polyvinyl chloride (PVC)/clay nanofiber composites with various contents were fabricated by the electrospinning process. The morphology, porosity, density, and mechanical properties of the nanofiber mats were investigated. In addition, PVC/clay nanofiber mats were characterized by Fourier transform infrared spectroscopy, differential scanning calorimetry, and thermogravimetric analysis.

Mangiferin as New Potential Anti-Cancer Agent and Mangiferin-Integrated Polymer Systems-A Novel Research Direction.

For a long time, the pharmaceutical industry focused on natural biologically active molecules due to their unique properties, availability and significantly less side-effects. Mangiferin is a naturally occurring C-glucosylxantone that has substantial potential for the treatment of various diseases thanks to its numerous biological activities. Many research studies have proven that mangiferin possesses antioxidant, anti-infection, anti-cancer, anti-diabetic, cardiovascular, neuroprotective properties and it also increases immunity.

Breast cancer detection by ATR-FTIR spectroscopy of blood serum and multivariate data-analysis.

Detection of breast cancer has particular importance for the diagnosis of cancer diseases. This is the most common type of cancer among women. Breast cancer is a malignant tumor of the glandular tissue of the breast.

Films Based on a Blend of PVC with Copolymer of 3-Hydroxybutyrate with 3-Hydroxyhexanoate.

Polymeric packaging materials are one of the factors of environmental pollution. Reducing the environmental burden is possible by increasing the environmental friendliness of packaging materials. In this work, we study polymer films based on polyvinyl chloride (PVC) with a copolymer of 3-hydroxybutyrate with 3-hydroxyhexanoate P (3-GB) (3-GG) with different component ratios.