Publications by authors named "Mayuna Suenaga"
Bacteria in certain genera can produce "bacterial polyynes" that contain a conjugated C≡C bond starting from a terminal alkyne. Protegenin A is a derivative of octadecanoic acid that contains an ene-tetrayne moiety. It was discovered in Cab57 and exhibits strong antioomycete and moderate antifungal activity.
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- Some bacteria produce unique compounds called bacterial polyynes, which they use as chemical weapons against other organisms.
- Cab57, a biocontrol agent, has an orphan gene cluster for these compounds, known as protegenins, which were characterized in this study.
- The study found that protegenins A-D have distinct chemical structures and exhibit varying levels of antioomycete activity, and their production is regulated by bacterial signaling systems and influenced by environmental conditions.