Publications by authors named "Mayumi Yuda"
Background: As the life expectancy of people living with human immunodeficiency virus (HIV) (PLWH) has improved, chronic disease burden and polypharmacy have increased in PLWH. Simplification of the antiretroviral therapy (ART) regimen for PLWH has become crucial. The real-world treatment patterns and medication persistence of the 2-drug single-tablet regimen (STR), dolutegravir/lamivudine (DTG/3TC), compared to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) prescribed were investigated.
View Article and Find Full Text PDFBackground: Research has found a COVID-19 pandemic-related impact on HIV medical services, including clinic visits, testing, and antiviral therapy initiation in countries including Japan. However, the change in trend for HIV/AIDS testing during the COVID-19 pandemic has not been explored extensively in the Japanese population.
Objective: This infodemiology study examines the web-based search interest for two types of HIV tests, self-test kits and facility-based tests, before and during the COVID-19 pandemic in Japan.
Introduction: Risk factors for severe COVID-19 associated with people living with HIV (PLWH) have not been well studied in Japan. In this study, we aim to reveal how having AIDS and comorbidities affect adverse COVID-19 outcomes.
Methods: This observational, retrospective study examined the clinical outcomes for PLWH hospitalized as COVID-19 inpatients in Japan, using data extracted from hospitals with the Diagnosis Procedure Combination (DPC) system between January 2020 and December 2021.
Article Synopsis
- The study investigates if the rise in syphilis cases in Japan is linked to new infections in people living with HIV (PLWH).
- Data from the Japanese National Database between 2009-2018 showed overall syphilis cases increasing while syphilis among PLWH remained stable at about 2%.
- The proportion of syphilis cases in PLWH decreased over time, indicating that the current syphilis resurgence in Japan is not due to this population's infections.
To report the status of switch rates and time-to-switch of antiretroviral therapy (ART) regimens by evaluating anchor drug classes and common switching patterns in Japanese people living with human immunodeficiency virus (HIV, PLWH). This cross-sectional cohort study extracted data of 28,089 PLWH from the National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB), which contains data representing the entire population of Japan. PLWH with first prescription records of ART administered between January 2011 and March 2019 were identified (n = 16,069).
View Article and Find Full Text PDFObjectives: Comorbidities are associated with a high burden of disease in people living with HIV (PLWH). The objective was to investigate the prevalence of chronic comorbidities and use of co-medications in PLWH in Japan.
Methods: This study retrospectively analysed clinical information from PLWH receiving antiretroviral therapy (ART) between April 2009 and March 2019.
Article Synopsis
- * Analysis of the National Database of Health Insurance Claims reveals that 42.5% of newly diagnosed HIV-positive patients also had a diagnosis of syphilis between 2011 and 2018.
- * The findings indicate that many syphilis patients were not tested for HIV, and a notable number of HIV patients still contracted syphilis after their diagnosis, underlining the need for better education on STD testing for those newly diagnosed with HIV.