Impact of the multidisciplinary antimicrobial stewardship team intervention focusing on carbapenem de-escalation: A single-centre and interrupted time series analysis.

Background: As a result of the constant increase in carbapenem resistance amongst gram-negative bacteria in several countries, the inappropriate use of carbapenems must be reduced. Antimicrobial stewardship programmes (ASPs) aim to improve carbapenem usage by implementing interventions, including the promotion of the de-escalation (DE) strategy. Thus, this study aimed to evaluate the impact of this strategy on carbapenem use based on a clear definition of DE.

[Importance of microbial test for vaginal secretion from a pregnant women].

As part of prenatal care, vaginal gram-stained smear was evaluated on 318 pregnant women at our hospital. Nugent's scoring was done by Gram staining, and in comparison with normal score group and high score group, the incidence of perinatal abnormalities was higher to the latter group. Therefore, routine examination of vaginal gram-stained smear is recommended in pregnant woman.