Ginger facilitates cell migration and heat tolerance in mouse fibroblast cells.

The components of ginger root ( Roscoe) are widely used for various medicinal purposes. Several bioactive compounds have been identified in ginger, including 6‑, 8‑ and 10‑gingerols, and 6‑shogaol, which are agonists of the thermo‑sensors transient receptor potential (TRP) cation channel subfamily V member 1 and TRP ankyrin 1. Our previous study demonstrated that ginger powder may affect human metabolism .

Sub-Chronic Consumption of Dark Chocolate Enhances Cognitive Function and Releases Nerve Growth Factors: A Parallel-Group Randomized Trial.

Previous research has shown that habitual chocolate intake is related to cognitive performance and that frequent chocolate consumption is significantly associated with improved memory. However, little is known about the effects of the subchronic consumption of dark chocolate (DC) on cognitive function and neurotrophins. Eighteen healthy young subjects (both sexes; 20-31 years old) were randomly divided into two groups: a DC intake group ( = 10) and a cacao-free white chocolate (WC) intake group ( = 8).

Preparation of α1- and α2-isomers of mono-Ru-substituted Dawson-type phosphotungstates with an aqua ligand and comparison of their redox potentials, catalytic activities, and thermal stabilities with Keggin-type derivatives.

Both the α1- and the α2-isomers of mono-ruthenium (Ru)-substituted Dawson-type phosphotungstates with terminal aqua ligands, [α1-P2W17O61Ru(III)(H2O)](7-) (α1-RuH2O) and [α2-P2W17O61Ru(III)(H2O)](7-) (α2-RuH2O), were prepared in pure form by cleavage of the Ru-S bond of the corresponding DMSO derivatives, [α1-P2W17O61Ru(DMSO)](8-) (α1-RuDMSO) and [α2-P2W17O61Ru(DMSO)](8-) (α2-RuDMSO), respectively. Redox studies indicated that α1-RuH2O and α2-RuH2O show proton-coupled electron transfer (PCET), and the Ru(III)(H2O) species was reversibly reduced to Ru(II)(H2O) species and oxidized to Ru(IV)([double bond, length as m-dash]O) species and further to Ru(V)([double bond, length as m-dash]O) species in aqueous solution depending on the pH. Their redox potentials and thermal stabilities were compared with those of the corresponding α-Keggin-type derivatives ([α-XW11O39Ru(H2O)](n-); X = Si(4+) (n = 5), Ge(4+) (n = 5), or P(5+) (n = 4)).

Oral intake of encapsulated dried ginger root powder hardly affects human thermoregulatory function, but appears to facilitate fat utilization.

The present study investigated the impact of a single oral ingestion of ginger on thermoregulatory function and fat oxidation in humans. Morning and afternoon oral intake of 1.0 g dried ginger root powder did not alter rectal temperature, skin blood flow, O2 consumption, CO2 production, and thermal sensation and comfort, or induce sweating at an ambient temperature of 28 °C.

Hydrothermal and solid-state transformation of ruthenium-supported Keggin-type heteropolytungstates [XW11O39{Ru(II)(benzene)(H2O)}]n- (X = P (n = 5), Si (n = 6), Ge (n = 6)) to ruthenium-substituted Keggin-type heteropolytungstates.

A new pathway for the preparation of mono-ruthenium (Ru)(iii)-substituted Keggin-type heteropolytungstates with an aqua ligand, [PW(11)O(39)Ru(iii)(H(2)O)](4-) (1a), [SiW(11)O(39)Ru(iii)(H(2)O)](5-) (1b) and [GeW(11)O(39)Ru(iii)(H(2)O)](5-) (1c), using [Ru(ii)(benzene)Cl(2)](2) as a Ru source was described. Compounds 1a-1c were prepared by reacting [XW(11)O(39)](n-) (X = P, Si and Ge) with [Ru(ii)(benzene)Cl(2)](2) under hydrothermal condition and were isolated as caesium salts. Ru(benzene)-supported heteropolytungstates, [PW(11)O(39){Ru(ii)(benzene)(H(2)O)}](5-) (2a), [SiW(11)O(39){Ru(ii)(benzene)(H(2)O)}](6-) (2b) and [GeW(11)O(39){Ru(ii)(benzene)(H(2)O)}](6-) (2c), were first produced in the reaction media, and then transformed to 1a, 1b and 1c, respectively, under hydrothermal conditions.

In vitro activities of azole antifungal agents against Propionibacterium acnes isolated from patients with acne vulgaris.

The Gram-positive bacterium Propionibacterium acnes is the causative agent of acne vulgaris. Antibiotics such as tetracycline and macrolide derivatives are used to treat this skin disease; however, the isolation frequency of antibiotic-resistant P. acnes has been increasing.