[Cancer Survivorship: the patient and medical care staff - how will society deal with cancer ?].

Instead of being preoccupied with treatment effectiveness, rates of survival, and asking how much longer will I live?, let us think in terms of how will I live my life the way I want to live it? In recent years, a new way of thinking called Cancer Survivorship has emerged in the United States, and has been drawing attention in Japan. Cancer Survivorship is a concept developed by a cancer patient support group in the United States in 1986, focusing on the experience of living with, through, and beyond cancer. Opposing society's narrow view of cancer patients as victims handed out a death sentence, Cancer Survivorship focuses on living life to the fullest from the time of cancer diagnosis until the moment of death,and works as a movement appealing to society to allow cancer survivors the right to live as they wish.

[International standards of cancer treatment: looking back on patient activities that led to the Basic Act for Anti-Cancer Measures].

The Basic Act for Anti-Cancer Measures was enacted in June 2006. Behind this act were the activities of patients who protested the state of cancer treatment in Japan, in which patients were cut off without appropriate chemotherapy or palliative care after being told "there is nothing more we can do to treat you" These patients called for hospitals to carry out cancer treatment at world standards, requested early approval of drugs, demanded the training of specialists able to provide expert chemotherapy, and proposed ways for the provision of accurate cancer-related information. Their message won sympathy in society, and led to the current reforms in cancer treatment.

Differential, histochemical and immunohistochemical changes in rat hepatocytes after isoflurane or sevoflurane exposure.

Differential, histochemical and immunohistochemical changes were observed in hepatocytes from immediately to 7 days after isoflurane or sevoflurane exposure (at H 0 to on Day 7) to study the process of development and recovery in anesthetic-induced hepatic injury. A total of 570 7-week-old male Sprague-Dawley rats with or without phenobarbital treatment were exposed to isoflurane or sevoflurane in 100%, 21%, or 10% oxygen, or to 10% oxygen alone for 2h. In phenobarbital-treated rats, hepatocytes both with and without anesthetic exposure markedly changed in 10% oxygen at H 0.