Publications by authors named "Mayu Kajiye"
Article Synopsis
- Microtubule-associated protein A1/B1-light chain 3 (LC3)-associated phagocytosis (LAP) is a non-canonical autophagy process that helps in the maturation of phagosomes within macrophages, but its mechanisms are not fully understood.
- Recent research identified MORN2 as a critical component of LAP, aiding in the efficient formation of LC3-recruiting phagosomes, and experiments with MORN2-overexpressing macrophages showed increased LC3-II production and improved acidification of LAPosomes.
- MORN2 is partially degraded by the ubiquitin-proteasome system and its function in LAP is regulated through interactions with soluble SNARE proteins like SNAP-
