Bilateral diffuse iris atrophy after the use of oral clarithromycin.

Purpose: To report a newly recognised advert event of clarithromycin.

Methods: Retrospective, case report.

Results: A 30-year old female referred to our centre with bilateral diffuse iris atrophy after the use of oral clarithromycin for a pulmonary infection.

The use of bevacizumab in a multilevel retinal hemorrhage secondary to retinal macroaneurysm: a 39-month follow-up case report.

Purpose: The evaluation of long-term visual outcome after the use of bevacizumab for the management of multilevel hemorrhage due to retinal arterial macroaneurysm (MA).

Case Report: A 71-year-old hypertensive female presented with sudden reduction of visual acuity in her left eye (OS). Fundoscopy revealed an arterial macroaneurysm with preretinal and subretinal hemorrhage in the eye.

Peak intraocular pressure and glaucomatous progression in primary open-angle glaucoma.

Purpose: To evaluate the effect of 24-h peak intraocular pressure (IOP) on the progression of primary open-angle glaucoma (POAG) and the 24 h time points that best predict peak pressure.

Methods: A retrospective analysis of clinical data evaluating long-term glaucomatous progression in patients with POAG who were previously in a 24-h study of the authors (IOP readings at 2/6/10 A.M.

Spontaneous traumatic macular hole closure in a 50-year-old woman: a case report.

Introduction: Traumatic macular holes (TMH) are well-known complications of ocular contusion injury. Spontaneous closure occurs in approximately 50% of cases, but rarely after the age of thirty. We report a case of spontaneous closure of a full thickness macular hole due to a blunt trauma and we suggest possible mechanisms for this closure.

Disc swelling in abetalipoproteinemia: a novel feature of Bassen-Kornzweig syndrome.

Purpose: Abetalipoproteinemia is a very rare disease with multisystemic manifestations.

Methods: Retrospective, case report.

Results: We report a 9-year-old girl with a history of Bassen-Kornzweig syndrome diagnosed at the age of 3.

Intraocular pressure control over 24 hours using travoprost and timolol fixed combination administered in the morning or evening in primary open-angle and exfoliative glaucoma.

Purpose: To evaluate intraocular pressure (IOP) control over 24 hours using travoprost and timolol fixed combination (TTFC) administered in the morning or evening in primary open-angle and exfoliative glaucoma.

Methods: Patients were randomized to TTFC administered in either the morning or evening for 8 weeks. Previously treated patients underwent an untreated washout period of 4-6 weeks, after which baseline IOP was required to be > 25 mm Hg and < 38 mmHg (in two readings taken at 10.