Publications by authors named "Maysa Araujo Ferreira-Julio"
Endoscopic procedure using argon plasma coagulation (APC) promotes a progressive reduction in gastrojejunal anastomosis diameter. The present study aimed to evaluate the efficacy of the APC in patients with weight regain in the postoperative periods of gastric bypass. This was a randomized controlled trial conducted with 66 patients who were randomly assigned selected (using lottery method) and divided into two groups: study group (SG), 38 patients (APC treatment); and control group (CG), 28 patients (only endoscopy procedure).
View Article and Find Full Text PDFMatrix metalloproteinases (MMP) and their endogenous inhibitor, the tissue inhibitor of metalloproteinases (TIMP), are expressed in many different cell types and play an important role in physiologic and pathological degradation of extracellular matrix (ECM). Starting from these observations and considering the activation state of peripheral blood mononuclear cells (PBMCs) in obesity, we investigated the gene expression of metalloproteinases before and after Roux-en-Y gastric bypass (RYBG). The study was performed in the Ribeirão Preto Medical School University Hospital.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to examine the link between specific Single Nucleotide Polymorphisms (SNPs) in the DRD2 and BDNF genes and Binge Eating Disorder (BED) in patients who regained weight after bariatric surgery.
- Researchers evaluated 177 bariatric surgery patients, assessing anthropometric measurements, BED using questionnaires, and genotyping relevant SNPs through real-time PCR.
- Results showed that certain allele variants (CT and TT for DRD2 rs1800497; GA and AA for BDNF rs6265) were more common in patients with BED, suggesting these genetic factors increase the risk of BED, particularly in those who have experienced weight regain.
Background/aim: We studied the molecular pathogenesis of obesity, involving complex interactions between environmental and genetic factors, with a focus on the leptin gene. It was our aim to characterize the LEP -2548G>A leptin polymorphism and lipid profile in obese and normal-weight individuals.
Methods: A total of 212 individuals were divided into the study group including 136 obese patients (body mass index, BMI≥30) and the control group with 76 normal-weight individuals (BMI>18.