Publications by authors named "Mayra R Santos"
Refractory pyoderma gangrenosum associated with rheumatoid arthritis successfully treated with upadacitinib. Comments on: "JAK inhibitors: a novel, safe, and efficacious therapy for pyoderma gangrenosum".
Mayra Rabelo Dos Santos Mayra Ianhez Bruno Nazeozeno Ribeiro Boaventura Braz de Queiroz Helio Amante Miot
Int J Dermatol
November 2023
Article Synopsis
- The study investigates the hypothesis that essential tremor (ET) may be related to hyperactivity in the posterior putamen, contrasting traditional views that focus on the olivocerebellar system.
- A rat model of ET was used, with groups undergoing either surgery to remove sections of the posterior striatum or sham procedures, followed by administration of harmaline to induce tremors for assessment.
- Results showed significant tremor reduction in the experimental group that had surgery, suggesting the posterior striatum's involvement in ET and supporting the proposed hypothesis.