Inhibition of Drp1-dependent mitochondrial division impairs myogenic differentiation.

Mitochondria are dynamic organelles forming a tubular network that is continuously fusing and dividing to control their morphology and functions. Recent literature has shed new light on a potential link between the dynamic behavior of mitochondria and muscle development. In this study, we investigate the role of mitochondrial fission factor dynamin-related protein 1 (Drp1) in myogenic differentiation.

Late cardiopulmonary and musculoskeletal exercise performance after repair for total anomalous pulmonary venous connection during infancy.

Objectives: We evaluated cardiopulmonary function at rest and during exercise in children after surgical repair for total anomalous pulmonary venous connection.

Background: Long-term assessment of cardiopulmonary function during exercise in children after repair for total anomalous pulmonary venous connection during infancy is limited.

Methods: Resting lung function and cardiopulmonary function during maximal ramp cycle ergometry were evaluated in 27 patients (age = 11 +/- 4 years, 20 were male).

Healthcare utilization among women with physical disabilities.

Background: Current published data indicate barriers and deficiencies in healthcare for women with physical disabilities. Yet, information regarding the influence of secondary conditions and demographic variables on the actual utilization of general health and rehabilitative services is limited. This research examined this issue.