Publications by authors named "Mayra Alejandra Gomez-Govea"
Genetic Variants in the 3'UTR of and Genes and their Putative Effects on the microRNA Mechanism in Hereditary Breast and Ovarian Cancer.
María Marisela Sánchez-Chaparro Idalia Garza-Veloz Omar Alejandro Zayas-Villanueva Margarita L Martinez-Fierro Iván Delgado-Enciso Mayra Alejandra Gomez-Govea
Diagnostics (Basel)
May 2020
Article Synopsis
- Hereditary breast and ovarian cancer (HBOC) syndrome is primarily linked to mutations in specific genes, with focus on the genetic variations in 3'UTR regions that affect microRNA binding and regulation.
- A study involving blood samples from 50 HBOC patients and 50 controls identified nine polymorphisms in these regions, with three variants significantly increasing the risk of developing HBOC.
- The findings suggest that these genetic variants can influence microRNA binding, highlighting their role in the development of HBOC.
Bacterial metabolites with communicative functions could provide protection against stress conditions to members of the same species. Yet, information remains limited about protection provided by metabolites in Bacillus cereus and inter-species. This study investigated the effect of extracellular compounds derived from heat shocked (HS) and non-HS cultures of B.
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