Results of iliac stenting and aortofemoral grafting for iliac artery occlusions.

Objective: To compare long-term results of percutaneous iliac artery stenting (PCIS) with aortobifemoral (ABF) grafting for patients with symptomatic iliac artery occlusions.

Methods: A retrospective review of 229 patients (January 2000 to December 2011) with symptomatic iliac artery occlusions was performed. In 100 patients, 103 PCIS procedures were performed, and 101 patients underwent ABF grafting.

Toll-like receptor 9 signaling is critical for early experimental deep vein thrombosis resolution.

Objective: Toll-like receptors (TLR) bridge innate immunity and host responses, including inflammation. Sterile inflammation such as a venous thrombus (Vt) may involve TLR signaling, including TLR9.

Methods And Results: TLR9 signaling on thrombus resolution was investigated using a mouse model of stasis Vt.

Vein wall remodeling after deep vein thrombosis: differential effects of low molecular weight heparin and doxycycline.

Background: Venous thrombus resolution sets up an early intense inflammatory reaction, from which vein wall damage results. Tissue response to injury includes matrix metalloproteinase (MMP) activation and extracellular matrix protein turnover. This study sought to determine the effect of exogenous MMP inhibition and its potential attenuation of early vein wall injury.