Publications by authors named "Mayker L D Miranda"

has been widely known due to its therapeutic properties. Tuberculosis is a deadly infectious disease caused predominantly by . Other respiratory diseases may also be caused by nontuberculous mycobacteria.

View Article and Find Full Text PDF

This study reports on the chemical composition and antileishmanial and anticandidal activities of volatile oils (VOs) of Schinus molle dried leaves (SM), Cinnamomum cassia branch bark (CC) and their blends. Major constituents of SM were spathulenol (26.93 %), β-caryophyllene (19.

View Article and Find Full Text PDF

Benth is a Brazilian medicinal plant (, in Brazilian Portuguese). This paper aims to determine the volatile composition and antibacterial activities of hexane extract from seeds (HE-PP). Antibacterial activities were screened by the microdilution broth method in 96-well culture plates and MIC values were expressed as µg/mL.

View Article and Find Full Text PDF

Citrus canker, which is caused by , is a severe disease that affects citrus plants worldwide. This paper aimed to compare, for the first time, the chemical composition and anti- activities of essential oils from fresh and dry leaves (EO-FL and EO-DL, respectively). Anti- activity of spathulenol, the major constituent of oils, was also evaluated.

View Article and Find Full Text PDF

This study aimed to investigate the chemical composition as well as the antibacterial, antiparasitic, and cytotoxic potentialities of the Brazilian root essential oil (CZ-EO) In addition, CZ-EO cytotoxicity to LLCMK adherent epithelial cells was assessed. The major compounds identified in CZ-EO were khusimol (30.0 ± 0.

View Article and Find Full Text PDF

This article aims to investigate volatile constituents and antiacetylcholinesterase, antileishmanial and antiproliferative activities of hexane extracts from fruit (unripe bode pepper 'HE-UB' and ripe little beak pepper 'HE-RB'). HE-UB and HE-RB were screened by the microplate assay method to determine their antiacetylcholinesterase activity. Both exhibited inhibitory potential, i.

View Article and Find Full Text PDF

This paper aims to investigate, for the first time, physicochemical characteristics and antioxidant capacity of ripe and unripe fruit. In addition, essential oil was extracted from fresh leaves (PM-EO) collected in dry and rainy seasons to investigate the influence of seasonality and, after that, to evaluate its antifungal activity on mycelial growth of . Both GC-FID and GC-MS analyses revealed that major components determined in PM-EO were β-caryophyllene (20.

View Article and Find Full Text PDF

Candidiasis therapy, especially for candidiasis caused by non- species, is limited by the relatively reduced number of antifungal drugs and the emergence of antifungal tolerance. This study evaluates the anticandidal activity of 41 plant-derived products against species, in both planktonic and biofilm cells. This study also evaluates the toxicity and the therapeutic action of the most active compounds by using the model.

View Article and Find Full Text PDF

species have been appreciated for their edible fruits and medicinal properties. This paper aims to investigate the chemical composition and antileishmanial, antifungal and antiproliferative activities of essential oil from aerial parts of (EP-EO). The oil showed strong antileishmanial activity against promastigote forms of (IC = 2.

View Article and Find Full Text PDF

is a tree species that naturally occurs in the Atlantic Forest, Brazil. This paper aims to investigate the chemical composition and antibacterial, antileishmanial and antiproliferative activities of essential oil from leaves (NM-EO). It displayed high antibacterial activity against , and .

View Article and Find Full Text PDF

In Brazilian folk medicine, is used to treat inflammatory conditions and to hasten wound repair. This paper aims to investigate the chemical composition and the antibacterial effects of the essential oils (EOs) obtained from leaves and ripe and unripe fruits against a representative panel of oral pathogens. The GC-FID and GC-MS analysis revealed that the major components determined in essential oils were myrcene (59.

View Article and Find Full Text PDF

Even though essential oils from Piper aduncum (Piperaceae) have different biological activities, little is known about their application to agricultural areas. White mold is a plant disease caused by the phytopathogen Sclerotinia sclerotiorum, which needs to be controlled by alternative measures. This study aimed at evaluating the effect of essential oils from P.

View Article and Find Full Text PDF

Leishmaniasis is an endemic disease caused by protozoa of the genus Leishmania, which affects around two million people worldwide. One major drawback in the treatment of leishmaniasis is the emergence of resistance to current chemotherapeutics. Medicinal and aromatic plants constitute a major source of natural organic compounds.

View Article and Find Full Text PDF

Tooth decay is a major public health problem which affects a large number of people in several countries. Even though more than 700 bacterial species have been detected in the oral cavity, Streptococcus and Lactobacillus stand out as the genera that cause tooth decay and other periodontal diseases. In this study, essential oils from Citrus aurantifolia leaves (CL-EO) and fruit peel (CP-EO) were obtained by hydrodistillation by a Clevenger-type apparatus whereas their chemical composition was analyzed by gas chromatography-flame ionization detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS).

View Article and Find Full Text PDF

In this study, the chemical composition and antibacterial and antiproliferative potential of the essential oil obtained from fresh leaves of (PM-EO) against oral pathogens and human tumour cell lines were investigated for the first time. GC-FID and GC-MS analyses showed that -β-caryophyllene (30.9%), α-humulene (15.

View Article and Find Full Text PDF

Leishmaniasis and trypanosomiasis are globally widespread parasitic diseases which have been responsible for high mortality rates. Since drugs available for their treatment are highly hepatotoxic, nephrotoxic and cardiotoxic, adherence to therapy has been affected. Thus, the search for new, more effective and safer drugs for the treatment of these diseases is necessary.

View Article and Find Full Text PDF

We investigate the chemical composition and the antileishmanial and cytotoxic activities of the essential oils extracted from the leaves of (Nees) Mez (OD-EO) and (Vell) Rohwer (OO-EO). On the basis of GC-FID and GC-MS, α-eudesmol (20.9%), valencene (10.

View Article and Find Full Text PDF

Many essential oils (EOs) of different plant species possess interesting antimicrobial effects on buccal bacteria and antioxidant properties. Eugenia klotzschiana Berg (pêra-do-cerrado, in Portuguese) is a species of Myrtaceae with restricted distribution in the Cerrado. The essential oils were extracted through the hydrodistillation technique using a modified Clevenger apparatus (2 hours) and chemically characterized by GC-MS.

View Article and Find Full Text PDF