Publications by authors named "Maygane Ronsmans"
Both endotherms and ectotherms (e.g., fish) increase their body temperature to limit pathogen infection.
View Article and Find Full Text PDFFever is an evolutionary conserved defense mechanism which is present in both endothermic and ectothermic vertebrates. Ectotherms in response to infection can increase their body temperature by moving to warmer places. This process is known as behavioral fever.
View Article and Find Full Text PDFThe order Herpesvirales encompasses viruses that share structural, genetic, and biological properties. However, members of this order infect hosts ranging from molluscs to humans. It is currently divided into three phylogenetically related families.
View Article and Find Full Text PDFCyprinid herpesvirus 3 (CyHV 3) is causing severe economic losses worldwide in common and koi carp industries, and a safe and efficacious attenuated vaccine compatible with mass vaccination is needed. We produced single deleted recombinants using prokaryotic mutagenesis. When producing a recombinant lacking open reading frame 134 (ORF134), we unexpectedly obtained a clone with additional deletion of ORF56 and ORF57.
View Article and Find Full Text PDFCyprinid herpesvirus 3 (CyHV-3) causes a lethal disease in common and koi carp (Cyprinus carpio). The present study investigated the ability of CyHV-3 to infect common carp during the early stages of its development (from embryos to fingerlings) after inoculation by immersion in water containing the virus. Fish were inoculated at different times after hatching with a pathogenic recombinant CyHV-3 strain expressing luciferase.
View Article and Find Full Text PDFArticle Synopsis
- * This virus is important to fish industries because it can cause big economic problems, and researchers have been studying it since the 1990s.
- * The review talks about new findings in CyHV-3 research, especially about how the virus interacts with carp.
Article Synopsis
- Cyprinid herpesvirus 3 (CyHV-3) causes a serious disease in common and koi carp.
- A specific gene, ORF134, was studied and found to be a common protein in the virus that doesn't help it reproduce or make fish sick.
- The experiments using different virus types showed that fish got sick the same way no matter if the ORF134 gene was missing or present.
Article Synopsis
- - Cyprinid herpesvirus 3 (CyHV-3) causes a deadly and highly contagious disease in common and koi carp, primarily entering through the skin when fish immerse in contaminated water.
- - The study discovered that removing skin mucus and creating lesions enhanced the entry of CyHV-3, demonstrating that mucus acts as a barrier against the virus.
- - Mucus extract was found to reduce the virus's infectivity in a lab setting, emphasizing the skin mucus's critical role in the fish's innate immune defense against viral infections.