INTRODUCTION Mortality analysis based on a single cause of death is not, in most cases, fully informative. There are several more illuminating procedures using a multiple cause of death approach; these are little known and rarely used in Cuba. The simplest of these methods, while methodologically limited, consists of summing all deaths from a specific cause mentioned on death certificates, regardless of whether the cause is listed as underlying or contributing.
View Article and Find Full Text PDFBackground: Cuba has a new pneumococcal conjugate vaccine candidate (PCV7-TT). This study evaluates the safety and immunogenicity in healthy infants using 2p+1 vaccination schedule.
Methods: A phase I, controlled, randomized and double blind clinical trial was designed.
Background. In Cuba, the Ma-Pi 2 macrobiotic diet has shown positive results in 6-month assays with type 2 diabetic patients. The objective of this study was to assess the influence of this diet at short and medium terms.
View Article and Find Full Text PDFDuring the first six-month period of 2001, a descriptive cross-sectional study of carriage in healthy children attending a day-care center in Havana City was performed. The objective was to find out the prevalence of potentially pathogenic bacteria and its association with possible risk factors. The design took into account the international and domestic regulatory bioethical requirements.
View Article and Find Full Text PDFThe epidemiological markers of Neisseria meningitidis strains isolated from carriers in Cuba for 20 years (1982-2002) were investigated. There were identified the serogroups, serotypes, subtypes and immunotypes of 331 strains corresponding to 2 different stages: epidemic (1982-1992) and postepidemic (1993-2002). A predominance of serogroup B (67.
View Article and Find Full Text PDFA randomized, controlled and double-blind study was conducted in young adults aged 18-20 aimed at evaluating the reactogenecity and immunogenecity of vaz-TyVi, a vaccine of polyssacharide Vi from Salmonella typhi. They were distributed into 3 groups: immunized with a dose of Vax-TyVi (Finlay Institute), TYPHIM Vi (Pasteur-Mérieux) or vax-TET (tetanic toxoid). Serum samples were taken before and 21 days after immunization.
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