Publications by authors named "Mayara Calixto Silva"

Despite legal safeguards, the Yanomami community faces challenges such as unauthorized incursions by gold miners, resulting in environmental degradation, particularly from mercury. This jeopardizes the health and food security of indigenous individuals, especially due to the consumption of contaminated fish. Ethnic and racial disparities persist in indigenous healthcare, marked by troubling health indicators such as malnutrition, anemia, and infectious diseases.

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Endometriosis presents a pro-inflammatory microenvironment influenced by cytokines, such as interleukin (IL)-8, which expression may be influenced by genetic polymorphisms. Therefore, we aimed to investigate the role of interleukin (IL)-8 rs4073 polymorphism in endometriosis' development and its related symptoms. A case-control study was conducted with 207 women with endometriosis and 193 healthy controls.

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Article Synopsis
  • The study focused on patient care for COVID-19 in a Brazilian referral center, analyzing factors affecting mortality, length of stay, and diagnostic outcomes during May 2020 with a sample size of 1,100 patients.
  • 76% of patients tested positive for COVID-19, primarily through RT-qPCR, revealing a high prevalence of hypertension, diabetes, and obesity among individuals, especially those aged over 52.
  • Key findings indicated that age, pulmonary impairment, and hypertension significantly impacted patient mortality and hospitalization duration, emphasizing the importance of timely sample collection for accurate diagnosis.
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Genetic polymorphisms involved in mercury toxicokinetics and toxicodynamics may be associated with severe mercury toxicity. This study aimed to investigate the impact of an polymorphism on chronic mercury exposure and the health situation of indigenous children from the Brazilian Amazon. One-hundred-and-three indigenous children (under 15 years old) were included and genotyped (rs1800435) using a TaqMan validated assay.

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