Aqueous cytokine changes associated with Posner-Schlossman syndrome with and without human cytomegalovirus.

Aim: To study the differences in aqueous cytokines in Posner-Schlossman Syndrome (PSS) patients with and without human cytomegalovirus (CMV) DNA in the aqueous humor.

Methods: This is a prospective study. Fifty-three uveitis patients with clinical signs of PSS were enrolled and aqueous humor samples were collected.

Comparison of aqueous humor cytokine and chemokine levels in diabetic patients with and without retinopathy.

Purpose: To compare the aqueous humor levels of proinflammatory and angiogenic factors of diabetic patients with and without retinopathy.

Methods: Aqueous humor was collected at the start of cataract surgery from diabetic subjects and non-diabetic controls. The presence and severity of diabetic retinopathy were graded with fundus examination.

Aqueous cytokine and chemokine analysis in uveitis associated with tuberculosis.

Purpose: The aim of this study was to study the aqueous cytokine and chemokine composition in patients with uveitis associated with tuberculosis (TAU).

Methods: We present a prospective case series of consecutive new patients with active uveitis presenting at a single tertiary center (January 1, 2008-January 1, 2010). Patients with no ocular pathology other than cataracts were enrolled as non-inflammatory controls.

Expression profile of inflammatory cytokines in aqueous from glaucomatous eyes.

Purpose: To determine the proinflammatory cytokine profile of aqueous humor from glaucomatous eyes.

Methods: Aqueous humor samples were prospectively collected from 38 eyes (26 primary open angle glaucoma [POAG] and 12 primary angle closure glaucoma [PACG] eyes) of 37 medically treated glaucoma patients and 23 cataract subjects recruited in an institutional setting in this case-controlled study. The main outcome measure was to quantify the levels of 29 inflammatory cytokines in the aqueous of glaucoma and cataract subjects using a multiplexed cytokine analysis.