National seroprevalence and trends in herpes simplex virus type 1 in the United States, 1976-1994.

Objectives: The objectives of this study were to estimate national seroprevalence of herpes simplex virus type 1 (HSV-1), describe trends in seroprevalence, and examine correlates of infection.

Goal: The goal of this study was to measure the burden of HSV-1 infection in the U.S.