Publications by authors named "Maya Orlofsky"
Article Synopsis
- Adolescence is marked by significant behavioral and physiological changes, leading to increased stress vulnerability, a pattern observed in rodent studies comparing adolescent and adult responses to stress.
- The study used juvenile and adult male and female rats to assess how they reacted to footshock stress, measuring hormone levels and cytokine expression in various brain regions important for stress response.
- Results showed that adolescent rats had blunted immune responses compared to adults, particularly with the IL-1 signaling system, indicating developmental differences in stress response mechanisms based on age and sex.
