Publications by authors named "Maya Loot"
Purpose: Scoliosis is an abnormality which causes anterior trunk asymmetry. The Truncal Anterior Asymmetry Scoliosis Questionnaire-adolescent idiopathic scoliosis (AIS) (TAASQ) measures the feeling about anterior trunk appearance in girls with AIS. It comprises 14 questions which evaluate frontal asymmetry of breasts, shoulders, and waist as well as behavioral attitude.
View Article and Find Full Text PDFInfantile hemangioma (IH) is the most common infantile tumor, affecting 5-10% of newborns. Propranolol, a nonselective β-adrenergic receptor (ADRB) antagonist, is currently the first-line treatment for severe IH; however, both its mechanism of action and its main cellular target remain poorly understood. Since betablockers can antagonize the effect of natural ADRB agonists, we postulated that the catecholamine produced in situ in IH may have a role in the propranolol response.
View Article and Find Full Text PDFObjectives: To describe our experience with prenatal counselling for surgical anomalies in a large volume center. The secondary aim is to suggest a list of prenatal abnormalities warranting counselling by a pediatric surgeon.
Methods: We reviewed all prenatal counselling consultations performed by the pediatric surgery team between January 1st, 2015 and December 31st, 2016.
Article Synopsis
- - Propranolol, a drug used for treating severe infantile hemangiomas (IH), has shown potential antitumor effects in some malignant tumors, but its mechanism of action remains unclear due to a lack of suitable tumor models.
- - Researchers created a responsive tumor model using immunodeficient mice and identified Aquaporin-1 (AQP1) as a key protein that mediates the tumor growth inhibition caused by propranolol.
- - Functional studies revealed that AQP1 is found in a specific layer of cells within IH and is crucial for the response to propranolol, suggesting that interactions between vascular cells and stromal telocytes enhance the drug's effectiveness.
Objective: Congenital haemangiomas (CHs) are rare, benign vascular tumours that are fully developed at birth. Three subtypes of CHs have been described based on clinical behaviour: rapidly involuting CHs (RICHs), non-involuting CHs (NICHs) and partially involuting CHs (PICHs). We explore in our study clinical, evolutionary and paraclinical characteristics of the three CH subtypes.
View Article and Find Full Text PDFBackground: Since 1987 we have run a Dermatologic Surgical Paediatric Outpatient Clinic (DSPOC) within the Children's Hospital in Bordeaux.
Objective: We analyse the consequences of an audit survey concerning the management of patients with congenital nevi (CN) seen at this clinic.
Methods: We reviewed the cases of 192 children examined and photographed at the DSPOC during the period January 1990-December 1997.