Impact of alcohol on the progression of HCV-related liver disease: A systematic review and meta-analysis.

Background & Aims: Despite a marked reduction in new cases of cirrhosis caused by HCV infection, over 500,000 new cirrhosis cases in this category were estimated globally in 2019. This contribution quantifies the relationship between alcohol use and the progression of liver disease in people with HCV infections.

Methods: The causal impact of different levels of alcohol use on cirrhosis has previously been established.

Alcohol use disorders and the risk of progression of liver disease in people with hepatitis C virus infection - a systematic review.

Liver cirrhosis and other chronic liver diseases are usually compartmentalized into separate categories based on etiology (e.g., due to alcohol, virus infection, etc.