Publications by authors named "Maya Berding"
Cell Oncol (Dordr)
October 2022
Article Synopsis
- Neuroblastomas, particularly those with high risk, often express telomerase activity, and compounds like 6-thio-2'-deoxyguanosine (6-thio-dG) can hinder the growth of these cancer cells.
- The study tested combinations of 6-thio-dG with traditional cancer drugs (etoposide, doxorubicin, ceritinib) on various neuroblastoma cell lines and mouse xenograft models, finding strong anti-tumor effects from 6-thio-dG combined with etoposide or doxorubicin, but not with ceritinib.
- The findings suggest that targeting telomerase can enhance the effectiveness of existing chemotherapy drugs, indicating a potential
