Evaluation of a Novel Cryoprobe for Atrial Ablation in a Chronic Ovine Model.

Purpose: Cryoablation is used in the treatment of atrial fibrillation and other cardiac arrhythmias. This study evaluated a novel 10-cm flexible nitrous oxide cryoprobe in an ovine model of atrial ablation.

Description: Six sheep were anesthetized, underwent a left thoracotomy, and were placed on cardiopulmonary bypass.

Impact of a refined advanced design for left atrial appendage exclusion.

Objectives: Exclusion of the left atrial appendage has been proposed to reduce the risk of stroke in patients with atrial fibrillation. The aim of this study was to evaluate the feasibility and efficacy of the AtriClip PRO·V device (AOD2), now in development, for left atrial appendage exclusion in a canine model.

Methods: The newest AtriClip design comprises a dual-spring mechanism that allows the clip to open into a 'V' shape while still providing equivalent force along the length of the beam.