Cutaneous leishmaniasis (CL) is common in rural Latin America, with around 55,000 cases yearly, and diagnosis often relies on basic methods like microscopy, which are not very effective.
A new method called recombinase-polymerase-amplification (RPA-LF) was tested in Peru, showing 91.2% sensitivity and 93% positive predictive value when compared to the standard kDNA-PCR test.
Although RPA-LF shows promise as a point-of-care testing option, further refinement and validation are needed for its widespread use in resource-limited areas.