Modulation of Cytoskeleton, Protein Trafficking, and Signaling Pathways by Metabolites from , and Plant Families.

One promising frontier within the field of Medical Botany is the study of the bioactivity of plant metabolites on human health. Although plant metabolites are metabolic byproducts that commonly regulate ecological interactions and biochemical processes in plant species, such metabolites also elicit profound effects on the cellular processes of human and other mammalian cells. In this regard, due to their potential as therapeutic agents for a variety of human diseases and induction of toxic cellular responses, further research advances are direly needed to fully understand the molecular mechanisms induced by these agents.

Utilization of lean project management principles and health informatics to reduce operating room delays in a vascular surgery practice.

Objectives: Perioperative inefficiency can increase cost. We describe a process improvement initiative that addressed preoperative delays on an academic vascular surgery service.

Methods: First case vascular surgeries from July 2019-January 2020 were retrospectively reviewed for delays, defined as late arrival to the operating room (OR).

The surgical debrief: Just another checklist or an instrument to drive cultural change?

Introduction: Post-procedural debrief is recommended to improve patient safety. We examined operating room (OR) clinicians' perceptions of the impact of a multi-disciplinary debrief on OR culture.

Methods: A survey was administered to 182 OR clinicians at a major academic medical center.