Synopsis of recent research by authors named "Maxwell Hogue"
- Maxwell Hogue's research primarily focuses on the synthesis and biological implications of modified inositol analogues, particularly azido inositol (InoAz) analogues, which are significant for various cellular functions and metabolic processes.
- In his 2020 publication, Hogue demonstrated an innovative methodology using Ferrier carbocyclization for the efficient synthesis of enantiopure InoAz analogues, overcoming traditional challenges associated with their production.
- Additionally, his 2017 study linked nutrient sensing and redox stress signaling through the O-GlcNAcylation of KEAP1, revealing a previously unrecognized connection between O-GlcNAc transferase inhibition and the activation of NRF2, crucial for managing oxidative stress responses.
