Publications by authors named "Maxwell Boyle"

Peripheral neuropathic pain is common in patients with peripheral nerve injury and can significantly impact both their function and quality of life. There is a wide variety of non-interventional treatment approaches, including pharmacologic therapy, physical/occupational therapy, modalities (therapeutic, mechanical, thermal, etc.), psychology, and lifestyle modification.

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Introduction: Cephalomedullary nail (CMN) length for intertrochanteric femur fractures without subtrochanteric extension has been an ongoing debate. The authors hypothesize that increasing nail length would result in increasing surgical time, greater incidence of acute kidney injury (AKI), postoperative anemia, and blood loss requiring transfusion due to increased intramedullary reaming and pressurization of the canal with nail insertion.

Methods: A retrospective chart review of patients aged 65 years or older who underwent CMN for low-energy intertrochanteric femur fractures from 2010 to 2018 was undertaken.

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Article Synopsis
  • - Hypercoagulable disorders (HCDs) can be genetic or developed over time, both increasing the risk of dangerous blood clots known as venous thromboembolic events (VTEs).
  • - Many patients with HCD only learn about their condition after experiencing complications from surgery.
  • - It's advised that anyone with concerns about HCD be referred to a hematology specialist for proper evaluation and treatment; additionally, using tourniquets in surgeries for HCD patients is discouraged due to potential risks.
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Subscapularis dysfunction and failure are the leading causes of complications of total shoulder arthroplasty (TSA). An approach to shoulder arthroplasty has been described that may improve exposure to the retroverted glenoid and spare the rotator cuff. This article details the 6-month clinical outcomes of the first 26 patients who underwent TSA using a posterior approach.

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Article Synopsis
  • Prostaglandin E (PGE) is involved in inflammation, making its inhibition an important target for drug development.
  • Diarylheptanoids are a type of compound that have shown effectiveness in inhibiting PGE, and this study focuses on synthesizing their analogues.
  • One of the leading compounds demonstrated a strong inhibitory effect on PGE with an IC value of 0.56 ng/µL, showing no toxicity up to a high concentration of 10 ng/µL.
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