[Survival rate of laryngeal cancer patients treated in Brazil's Unified Health System - SUS, 2002-2010].

The scope of this article was to analyze the five-year survival rate among patients with laryngeal cancer treated in the Unified Health System in Brazil and its regions between January 2002 and June 2010. There is still scarce information in Brazil regarding the scale and survival rate of laryngeal cancer patients, which makes it difficult to adopt specific strategies for the control of the condition in the country. A retrospective cohort study based on the National Oncology Database was conducted, and the survival probability rate for laryngeal cancer according to age, sex and Brazilian regions/states was estimated using the Kaplan-Meier method.

Quality of life of women who underwent breast cancer treatment relative to sociodemographic, behavioral, and clinical factors.

Objective: Patients with cancer often undergo multiple extended treatments that decrease their quality of life. However, the quality of life of women with breast cancer after they undergo treatment remains underexplored in Brazil. Therefore, this study determined sociodemographic, behavioral, and clinical factors related to the post-treatment quality of life of women with breast cancer.

Breast cancer survival and the health system in Brazil: an analysis of public and private healthcare.

Background: The incidence of breast cancer is increasing globally; however, survival outcomes vary and are lower in developing countries.

Methods: We analyzed the 5- and 10-year survival rates for breast cancer according to the type of healthcare insurance (public . private) in a referral center for cancer care in the Brazilian southeast region.

Temporal trends in social security benefits for female breast cancer in Brazil.

The aim of this study was to assess temporal trends in disability benefits for breast cancer awarded to women by Brazil's National Social Security Institute. We conducted a time-series analysis of disability benefit incidence rates between 2007 and 2018 using joinpoint regression and data from the Unified Benefits Information System (SUIBE) and open access social security system database. The age-adjusted incidence rate increased by 6.

Histological and Immunohistochemical Characteristics for Hereditary Breast Cancer Risk in a Cohort of Brazilian Women.

Objective:  The study aimed to characterize the clinical, histological, and immunohistochemical profile of women with invasive breast cancer, according to the risk for Hereditary Predisposition Breast and Ovarian Cancer Syndrome in a Brazilian population.

Methods:  This is a retrospective study performed from a hospital-based cohort of 522 women, diagnosed with breast cancer treated at an oncology referral center in the Southeast region of Brazil, between 2014 and 2016.

Results:  Among the 430 women diagnosed with invasive breast cancer who composed the study population, 127 (29.

The increasing burden of pancreatic cancer in Brazil from 2000 to 2019: estimates from the Global Burden of Disease Study 2019.

Introduction: Pancreatic cancer is increasing worldwide. The burden of pancreatic cancer in Brazil and its states was analyzed and compared with that from the USA and China.

Methods: This is a descriptive study of the incidence and mortality estimates from the Global Burden of Disease 2019 study, from 2000 to 2019.

Trend of the Burden of Larynx Cancer in Brazil, 1990 to 2019.

Introduction: Larynx cancer is one of the most common head and neck cancers, whose main risk factors are smoking and alcohol use, and its occurrence and prognosis depend on adequate and timely preventive measures. This study aimed to investigate the burden of larynx cancer in Brazil and its states.

Methods: Using estimates from the Global Burden of Disease Study 2019, this study analyzed the trends of incidence, mortality, and disability-adjusted life years (DALYs) for larynx cancer between 1990 and 2019, besides the mortality-to-incidence ratio and the socio demographic index.

Inequalities in the burden of female breast cancer in Brazil, 1990-2017.

Background: Breast cancer is the most frequently diagnosed cancer in women and the leading cause of cancer death among females worldwide. In recent decades, breast cancer death rates have been stable or decreasing in more developed regions; however, this has not been observed in less developed regions. This study aims to evaluate inequalities in the burden of female breast cancer in Brazil including an analysis of interregional and interstate patterns in incidence, mortality and disability-adjusted life years (DALYs) rates from 1990 to 2017, and mortality-to-incidence ratio (MIR), and their association with the Socio-demographic Index (SDI).

The Global Burden of Disease Study Estimates of Brazil's Cervical Cancer Burden.

Background: Cervical cancer represents an important preventable cause of morbidity and mortality in developing countries such as Brazil. Investigating temporal evolution of a disease burden in the different realities of the country is essential for improving public policies.

Objective: To describe the national and subnational burden of cervical cancer, based on the estimates of the 2017 Global Burden of Disease study.

HELICOBACTER PYLORI INFECTION AND GASTRIC CANCER PRECURSOR LESIONS: PREVALENCE AND ASSOCIATED FACTORS IN A REFERENCE LABORATORY IN SOUTHEASTERN BRAZIL.

Background: Helicobacter pylori infection is the most important risk factor for gastric atrophy and intestinal metaplasia, both considered gastric cancer precursor lesions. Therefore, the investigation of the occurrence of H. pylori infection, precursor lesions and associated factors guides the adoption of specific strategies for the control this type of cancer.

The effect of redistribution of ill-defined causes of death on the mortality rate of breast cancer in Brazil.

The relevance of breast cancer for women has driven research about mortality of this disease. However, these studies are affected by problems generated by deaths due to ill-defined causes (IDC). To highlight distortions caused by IDC in studies that evaluate mortality, we calculated the age-standardized mortality rates of breast cancer, with and without adjustment for IDC for the years 1990, 2000, and 2010.

Interobserver reliability in the classification of pairs of records formed by probabilistic linkage of SISMAMA databases.

Introduction: The study assessed interobserver reliability in the classification of record pairs formed during probabilistic linkage of health-related databases, a key step in the methodology validation to be used in a larger on-going study on inequalities in the access to breast and cervical cancer control activities in Brazil (DAAC-SIS).

Methodology: The RecLink software was used to link two databases of the Breast Cancer Control Information System (SISMAMA) in the state of Minas Gerais, Brazil: a reference database, which included 301 screening mammograms with probable benign diagnosis (BI-RADS 3 category) recorded in October 2010, and a database comprising 158,517 mammograms registered in 2011. Subsequently, the 215 pairs of records that were not assigned the maximum RecLink score were independently classified as being true or false by ten independent evaluators from four participating centers.

Inequities in access to mammographic screening in Brazil.

Our objectives with this study were to describe the spatial distribution of mammographic screening coverage across small geographical areas (micro-regions) in Brazil, and to analyze whether the observed differences were associated with spatial inequities in socioeconomic conditions, provision of health care, and healthcare services utilization. We performed an area-based ecological study on mammographic screening coverage in the period of 2010-2011 regarding socioeconomic and healthcare variables. The units of analysis were the 438 health micro-regions in Brazil.

Incidence of rare cancers in the city of São Paulo, Brazil.

Introduction:: Rare cancers are a challenge for clinical practice as well as for epidemiology and public health. Studies on this subject are few and limited to the study of cases with scarce epidemiologic information. This study aimed to evaluate the incidence of rare cancers and to compare the demographic, anatomic, and histologic characteristics of rare and nonrare (common) cancers.

[Mammographic over-screening: evaluation based on probabilistic linkage of records databases from the Breast Cancer Information System (SISMAMA)].

The Brazilian Ministry of Health recommends biennial mammographic screening for women aged between 50 and 69 years. Since screening is opportunistic in the country, the actual periodicity varies. This study sought to test a methodology for estimating over-screening due to excessive periodicity, defined as a smaller than recommended interval between exams, and its association with socio-demographic characteristics.

[Racial disparity in 10-year breast cancer survival: a mediation analysis using potential responses approach].

The study's objectives were to investigate the association between race/color and 10-year survival in women with breast cancer and the role of staging as mediator. This was a hospital cohort with 481 women with invasive breast cancer diagnosed from 2003 to 2005. Comparisons were made between white and black women as to sociodemographic characteristics and staging, using the chi-square test, and 10-year survival, using Kaplan-Meier and Cox regression methods.

Survival Study of Triple-Negative and Non-Triple-Negative Breast Cancer in a Brazilian Cohort.

Objective: To analyze the clinical, pathological, and sociodemographic aspects between triple-negative breast cancer (TNBC) and non-TNBC in a Brazilian cohort and identify potential prognostic factors.

Methods: This hospital-based retrospective cohort study included 447 women with breast cancer treated at referral centers in Southeastern Brazil. Overall and disease-free survival were compared; prognostic factors were evaluated.

Mortality and years of life lost due to breast cancer attributable to physical inactivity in the Brazilian female population (1990-2015).

The aims of this study were as follows: to estimate the mortality and years of life lost, assessed by disability-adjusted life years (DALYs), due to breast cancer attributable to physical inactivity in Brazilian women; to compare the estimates attributable to physical inactivity and to other modifiable risk factors; and to analyse the temporal evolution of these estimates within Brazilian states over 25 years (1990-2015), compared with global estimates. Databases from the Global Burden of Disease Study for Brazil, Brazilian states, and other parts of the world were used. Physical inactivity has contributed to a substantial number of deaths (1990: 875; 2015: 2,075) and DALYs (1990: 28,089; 2015: 60,585) due to breast cancer in Brazil.

Functional status of patients with metastatic spinal cord compression.

Purpose: This prospective study was conducted to evaluate the functional status and clinical features of inpatients with metastatic spinal cord compression and to explore possible associated factors and the correlation with neurological deficits.

Methods: Cases were identified through an active search in the hospital units of the National Cancer Institute. For 47 patients, clinical and demographic characteristics were collected; functional status was measured by the Functional Independence Measure; modified Tokuhashi score was used to predict survival time; neurological deficits were measured using the American Spinal Injury Association Impairment Scale; and general condition was evaluated using the Karnofsky Performance Status Scale.

Factors associated with adherence and persistence to hormonal therapy in women with breast cancer.

Introduction: Hormonal therapy in breast cancer is essential to the transition from active treatment to care survival, because it improves long-term survival and provides a better quality of life. reducing hospital costs as well. However, adherence and persistence in the recommended treatment are important to achieve the desirable results.

[Breast cancer mortality in Brazilian municipalities and associated factorsMortalidad por cáncer de mama en municipios brasileños y factores asociados].

Objective: To analyze breast cancer mortality trends in Brazilian municipalities and assess the influence of socioeconomic and demographic factors on mortality rates.

Methods: Age-adjusted mortality rates were calculated for the periods centered in 1990, 2000, and 2010 and corrected for ill-defined causes of death. After that, panel data regression models were developed for analysis of the association between the factors of interest and the mortality rate from breast cancer in Brazilian municipalities.

Cause-specific mortality for 249 causes in Brazil and states during 1990-2015: a systematic analysis for the global burden of disease study 2015.

Background: Reliable data on cause of death (COD) are fundamental for planning and resource allocation priorities. We used GBD 2015 estimates to examine levels and trends for the leading causes of death in Brazil from 1990 to 2015.

Methods: We describe the main analytical approaches focused on both overall and specific causes of death for Brazil and Brazilian states.

Breast Cancer screening in Minas Gerais: assessment of data from information health systems of the Brazilian National Health System.

Objective: to assess the results of indicators related to the supply of mammography and level of adequacy of diagnostic confirmation for mammograms with suspicious findings of malignancy in Minas Gerais state and its health macroregions.

Methods: this is an evaluation study performed with data from the Breast Cancer Information System and the Outpatient Information System for the years 2010 and 2011.

Results: : the ratio of mammograms in women aged 50 to 69 years was of 0.