Multipath Projection Stereolithography for Three-Dimensional Printing Microfluidic Devices.

Although many lab-on-chip applications require inch-sized devices with microscale feature resolution, achieving this via current 3D printing methods remains challenging due to inherent trade-offs between print resolution, design complexity, and build sizes. Inspired by microscopes that can switch objectives to achieve multiscale imaging, we report a new optical printer coined multipath projection stereolithography (MPS) specifically designed for printing microfluidic devices. MPS is designed to switch between high-resolution (1× mode, ∼10 μm) and low-resolution (3× mode, ∼30 μm) optical paths to generate centimeter-sized constructs (3 × 6 cm) with a feature resolution of ∼10 μm.