Publications by authors named "Maximilian Vlad Muntean"

Article Synopsis
  • Perforator mapping is essential for planning microsurgical free flaps in breast reconstruction, with various mapping techniques available.
  • A study involving 33 patients showed that using Dynamic Infrared Thermography (DIRT) and Colour Doppler Ultrasonography (CDUS) can effectively identify perforators, potentially replacing Computed Tomography Angiography (CTA).
  • Results indicated a high confirmation rate of perforators detected by DIRT and CDUS, with DIRT being faster and equally accurate compared to CTA, suggesting that these methods could streamline preoperative assessment.
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  • The review highlights the significance of skin flap viability after mastectomy in immediate breast reconstruction and aims to compare current perfusion assessment methods.
  • Researchers analyzed data from four major scientific databases, including studies published in English over the last decade, resulting in a total of 58 relevant studies.
  • Indocyanine green angiography (ICG-A) is identified as the most preferred tool for assessing perfusion, especially in at-risk patients, while emerging technologies show potential for future use, emphasizing the importance of complementing these tools with clinical evaluation.
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Patient compliance in chronic illnesses is essential for disease management. This also applies to age-related macular degeneration (AMD), a chronic acquired retinal degeneration that needs constant monitoring and patient cooperation. Therefore, patients with AMD can benefit by being properly informed about their disease, regardless of the condition's stage.

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Since transcription factor Forkhead Box P3 (FoxP3) was identified as a specific regulatory T cell (Treg) marker, researchers have scrutinized its value as a potential novel therapeutic target or a prognostic factor in various types of cancer with inconsistent results. The present analysis was performed to assess the influence of Treg FoxP3 expression on the prognosis of primary melanoma and to evaluate the correlations with various clinicopathological prognostic factors. We analyzed all eligible patients with stage pT3 primary malignant melanomas treated in a tertiary cancer center.

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Article Synopsis
  • The keystone perforator island flap (KPIF) is becoming a popular choice in plastic surgery for reconstructing large and complex defects due to its simple harvesting technique and less risk of complications.
  • The study aims to investigate and document the tension-reducing effects of different types of KPIFs on wound closure, which could enhance understanding of their biomechanical benefits.
  • The experimental study used 12 porcine models to test 42 "unclosable" wounds, measuring intraoperative tissue tension during the application of various KPIF types.
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The era of artificial intelligence (AI) has revolutionized our daily lives and AI has become a powerful force that is gradually transforming the field of medicine. Ophthalmology sits at the forefront of this transformation thanks to the effortless acquisition of an abundance of imaging modalities. There has been tremendous work in the field of AI for retinal diseases, with age-related macular degeneration being at the top of the most studied conditions.

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Hidradenitis suppurativa is a disease with underestimated incidence, consequences and treatment difficulty. Regarded as a minor illness, for the patient it is disabling physically and socially, and for the doctor it is a challenge in choosing the appropriate treatment. We present the case of a 28-year-old man who presented with an advanced and persistent form of hidradenitis treated in a general surgery department.

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Background: Capsular contracture (CC) is the most common long-term complication of breast surgery with prosthesis. Leukotriene receptor antagonists (LRAs) have been tested as a potential treatment; however, mixed results have been observed.

Objectives: The aim of this study was to undertake a meta-analysis to clarify the treatment and prophylactic capabilities of LRAs in the management of CC.

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Achieving good aesthetic outcomes during immediate reconstruction in women with large ptotic breast presents a unique challenge for the reconstructive surgeon. We present our paradigm regarding immediate reconstruction in patients with large ptotic breasts, using the inferiorly based dermal flap. Ten patients with large ptotic breasts underwent mastectomy and immediate implant reconstruction at the "Prof.

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Purpose: Tumor infiltrating lymphocytes (TILs) in cutaneous malignant melanoma are classified as brisk, non-brisk or absent. Numerous studies suggest the presence of TILs, especially brisk, are associated with a lower rate of lymph node metastasis and with an improved overall survival (OS). Our purpose was to assess the value of TILs as a prognostic factor for the lymph node metastasis and survival in completely resected pT3 stage malignant melanoma patients.

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Aims: The high technical demands associated with perforator flaps demand a precise preoperative identification and evaluation of perforator vessels. Color Doppler Ultrasonography (CDU) and Dynamic Infrared Thermography (DIRT) are currently used for preoperative perforator mapping. Each individual technique has advantages and disadvantages.

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Flap monitoring technology has progressed alongside flap design. The highly variable vascular anatomy and the complexity associated with modern perforator flaps demands dynamic, real-time, intraoperative information about the vessel location, perfusion patterns and flap physiology. Although most surgeons still assess flap perfusion and viability based solely on clinical experience, studies have shown that results may be highly variable and often misleading.

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Background: Surgical therapy remains the most effective treatment modality in gastric cancer. The importance of multimodal treatment for advanced gastric cancer has contributed to the development of more accurate preoperative staging strategies. We examined the diagnostic accuracy of staging laparoscopy (SL) for abdominal metastases and the predictive value of SL for tumor resectability.

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