Publications by authors named "Maxime Taghavi"

Article Synopsis
  • - Acute kidney injury can often be a side effect of certain medications, including antibiotics like amoxicillin.
  • - A specific case is reported where a patient experienced acute renal failure twice due to amoxicillin, which was linked to an immuno-allergic reaction.
  • - The diagnosis was validated through kidney biopsy and was further confirmed when the patient was re-exposed to amoxicillin.
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  • * Researchers performed a retrospective analysis on 116 HD patients, finding that 32.7% had persistent aPL positivity, which was significantly linked to AVF maturation failure, independent of other complications like stenosis.
  • * The findings suggest for the first time a strong connection between aPL positivity and delayed or inadequate maturation of native AVFs, highlighting potential clinical implications for managing HD patients.
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Background: Froin's syndrome (FS) is a rare entity with uncertain prevalence and prognosis, defined by a pathognomonic triad: cerebrospinal fluid (CSF) xanthochromia, elevated protein levels in the CSF, and hypercoagulated CSF, usually obtained through lumbar puncturing below the level of a partial or complete spinal block.

Methods: We conducted a comprehensive review of the literature on FS from its first description in 1903 to December 2023, utilizing PubMed and Google Scholar, and included two new cases from our clinical practice.

Results: We describe two patients who suffered from Froin's syndrome secondary to spinal abscesses.

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  • Chronic beryllium disease (CBD) is an interstitial lung condition caused by inhaling beryllium particles, and it can often be confused with sarcoidosis but has distinct characteristics and complications.
  • A case involving a 60-year-old man revealed multi-organ involvement, with his kidney issues stemming from CBD rather than typical pulmonary symptoms, which were relatively mild.
  • The report emphasizes the need for healthcare providers to consider CBD as a potential diagnosis in patients exhibiting granulomatous diseases, especially when they present with related respiratory issues, despite the absence of classical lung symptoms.
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Catastrophic antiphospholipid syndrome (CAPS) is a rare and life-threatening condition characterized by the persistence of antiphospholipid antibodies and occurrence of multiple vascular occlusive events. CAPS currently remains a diagnostic challenge and requires urgent treatment. The diagnosis of CAPS is made difficult by classification criteria used as diagnostic criteria in clinical practice, knowledge derived from retrospective data and case reports, confounding clinical and biological features, and its rapid onset and mortality.

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Antiphospholipid antibody (aPL)-persistent positivity is frequent in hemodialysis (HD) patients. Native arteriovenous fistula (AVF) complications such as stenosis and thrombosis are among the most important causes of morbidity and mortality in hemodialysis patients. The association between aPL positivity and AVF thrombosis seems to now be well established.

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  • Crohn's disease is primarily an inflammatory bowel disease that can lead to various complications, including immunoglobulin A nephropathy (IgAN), which affects kidney health.
  • A case study highlights a young Crohn's patient who developed IgAN resulting in end-stage kidney disease and later discovered a rare and aggressive form of bladder cancer called urachal adenocarcinoma.
  • The case emphasizes the necessity of thorough and continuous medical follow-up for Crohn's patients, stressing regular screenings and interdisciplinary care to catch complications early.
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  • - The process of assessing transplant suitability is complex, requiring multiple evaluations and specialist opinions, as outlined in the KDIGO guidelines, prompting a re-evaluation of their relevance in the context of evolving medical practices, especially in oncology.
  • - The case study involves a 60-year-old woman with end-stage kidney disease stemming from prior rectal cancer treatment, leading to urological complications that complicate her kidney transplant options.
  • - Key considerations for her transplant candidacy include the long-term absence of cancer recurrence and the frail state of her urological anatomy, requiring a careful balance of risks, benefits, and a patient-centered decision-making approach.
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Scleroderma renal crisis is a severe complication of systemic sclerosis with a poor prognosis. Therefore, identifying precipitating factors is essential. Among known risk factors, only few are reversible.

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Objective: Antiphospholipid antibody (aPL) nephropathy (-N) can be challenging to recognize due to a lack of established classification or diagnostic criteria. As part of efforts to develop new antiphospholipid syndrome (APS) classification criteria (CC), the APS CC Renal Pathology Subcommittee aimed to better characterize the entity of aPL-N.

Methods: We used a 4-pronged approach that included (1) administering Delphi surveys to worldwide APS physicians to generate aPL-N terminology; (2) conducting a literature review to demonstrate the association of nephropathy with aPL and identify published aPL-N histopathological terminology and descriptions; (3) evaluating aPL-N terminology used in renal biopsy reports from an international patient registry; and (4) evaluating proposed kidney pathologic features for aPL-N by assessment of international Renal Pathology Society (RPS) members.

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Infective endocarditis (IE) due to non-HACEK (species other than ) bacteremia accounts for less than 2% of all IE cases but is proven to be associated with higher mortality, even more so in hemodialysis (HD) patients. Few data are available in the literature concerning non-HACEK Gram-negative (GN) IE in this immunocompromised population with multiple comorbidities. We report the atypical clinical presentation of an elderly HD patient diagnosed with a non-HACEK GN IE, namely , successfully treated with intravenous (IV) antibiotics.

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Background: Peritoneal dialysis (PD) depends upon a functioning and durable access to the peritoneal cavity. Many techniques exist to insert a peritoneal catheter, showing similar outcomes and benefits. Blind percutaneous insertion represents a bedside intervention predominantly performed by nephrologists requiring only local anesthesia, sedation and minimal transcutaneous access.

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Anuric hemodialyzed end-stage renal disease patients are prone to multiple complications and comorbidities and are therefore often treated with various medications. Adverse drug reactions and risk factors leading to them can be difficult to discern in such polymedicated patients. Most problems regarding low phosphate levels are frequently underdiagnosed in clinical practice and sometimes overlooked in these regularly hyperphosphatemic patients.

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Background: Peritonitis is a common complication of chronic peritoneal dialysis treatment contributing to both technique failure and/or death. Little is effectively known about the actual benefits of a continuous training program on peritonitis rates. In the present study, we measured the impact of our patients' training protocol on peritonitis rates.

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Article Synopsis
  • Acute granulomatous tubulointerstitial nephritis (GTIN) is a rare condition found in kidney biopsies, particularly when it presents with bilateral anterior uveitis (GBAU).
  • Differentiating between GTIN related to uveitis syndrome (TINU) and sarcoidosis is often difficult and can lead to complex diagnostic challenges.
  • The case study involves a confirmed GTIN with GBAU, and suggests a diagnostic plan while highlighting effective treatment of both kidney and eye symptoms using mycophenolate mofetil.
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Foreign bodies such as implanted cardiac devices are susceptible to infections and may be involved in infective endocarditis. Exposure to pathogens, by frequent use of intravascular accesses for hemodialysis (i.e.

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Article Synopsis
  • - Non-typhoidal Salmonella (NTS) disease can cause serious infections beyond digestive symptoms, particularly in older patients with weakened immune systems, leading to potentially life-threatening conditions like septic shock.
  • - In a study involving seven patients with invasive NTS (iNTS), some experienced severe secondary infections, including urinary tract issues and aortic aneurysms; treatment varied from medication to surgery, with mixed outcomes.
  • - The research highlights the challenging nature of iNTS, emphasizing the need for extended antimicrobial therapy and surgical intervention for secondary infections. It also stresses the importance of public health measures to prevent the spread of NTS and combat drug resistance.
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We report a case of hemolysis during a hemodialysis (HD) session in a 71-year-old man. His end-stage kidney disease is secondary to light-chain amyloidosis with renal involvement. Despite immunosuppressive treatment, his renal function continued to decline, and dialysis had to be initiated.

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Among peritoneal dialysis patients, peritoneal dialysis-related peritonitis is a well-known complication, but it can also be non-peritoneal dialysis-related (e.g. ruptured appendix).

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