Oral Immunotherapy for Hazelnut Allergy: A Single-Center Retrospective Study on 100 Patients.

Background: Oral immunotherapy (OIT) protects patients with IgE-mediated food allergies from food-induced allergic reactions due to accidental exposure and may improve their quality of life. This approach has never been evaluated for hazelnut, a major cause of food allergy in Europe.

Objective: To determine the proportion of hazelnut-desensitized patients after 6 months of OIT and to identify predictors of successful desensitization.

Phenotypical characterization of peanut allergic children with differences in cross-allergy to tree nuts and other legumes.

Background: Peanut allergy in children is often associated with allergies to tree nuts and/or legumes. The aim of this study was to analyze in cluster a cohort of children allergic to peanuts and assessed for cross-reactivity to nuts and legumes and to identify different phenotypes.

Methods: We included retrospectively 317 children with peanut allergy evaluated at the Allergy Unit of the Saint Vincent Hospital of Lille in the last 12 years.