Publications by authors named "Maxime Noriega"
Article Synopsis
- Mincle is a receptor that plays a vital role in the immune response by recognizing glycolipids, making it a potential target for new tuberculosis vaccines.
- The newly developed Martini 3 force field enhances the modeling of interactions between proteins and ligands, improving upon the earlier Martini 2 model.
- This research explores Mincle's interactions with glycolipids, highlighting key factors like loop flexibility and calcium ion regulation, which are crucial for understanding ligand recognition and affinity.
Fibronectin Leucine-rich Repeat Transmembrane (FLRT 1-3) proteins are a family of broadly expressed single-spanning transmembrane receptors that play key roles in development. Their extracellular domains mediate homotypic cell-cell adhesion and heterotypic protein interactions with other receptors to regulate cell adhesion and guidance. These in trans FLRT interactions determine the formation of signaling complexes of varying complexity and function.
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