Publications by authors named "Maxime Gilsoul"

Article Synopsis
  • The Zika virus (ZIKV) has been linked to severe birth defects, primarily traced to the Asian lineage, even though the African lineage shows higher transmissibility and danger in labs.
  • Recent experiments with low-passage ZIKV strains reveal that African variants are more easily spread by mosquitoes and are deadlier to both adult and fetal mice than Asian strains.
  • The study warns that African ZIKV strains could pose a significant public health risk because they might remain undetected, as they are more likely to cause fetal loss rather than noticeable birth defects.
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Juvenile myoclonic epilepsy (JME), a lifelong disorder that starts during adolescence, is the most common of genetic generalized epilepsy syndromes. JME is characterized by awakening myoclonic jerks and myoclonic-tonic-clonic (m-t-c) grand mal convulsions. Unfortunately, one third of JME patients have drug refractory m-t-c convulsions and these recur in 70-80% who attempt to stop antiepileptic drugs (AEDs).

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