Publications by authors named "Maxime Bredel"

Background: Necrotizing enterocolitis (NEC) is still one of the leading causes of neonatal death. The present study reports the data from a French case-control prospective multicenter study.

Methods: A total of 146 preterm neonates (PNs) with or without NEC were included.

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Non-alcoholic fatty liver disease (NAFLD) affects about 20-40% of the adult population in high-income countries and is now a leading indication for liver transplantation and can lead to hepatocellular carcinoma. The link between gut microbiota dysbiosis and NAFLD is now clearly established. Through analyses of the gut microbiota with shotgun metagenomics, we observe that compared to healthy controls, is depleted in patients with liver diseases such as NAFLD.

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Article Synopsis
  • Early azithromycin use after stem cell transplants can lead to higher relapse rates of blood cancers.
  • A study of 55 patients revealed four gut enterotypes, showing that specific gut bacteria and viruses relate to cancer remission or relapse.
  • The findings suggest that azithromycin affects gut ecosystems, influencing immune cell functions that may contribute to cancer relapse.
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Background: Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. IgA is mainly produced by the gut-associated lymphoid tissue (GALT). Both experimental and clinical data suggest a role of the gut microbiota in this disease.

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