Unraveling the Liver-Brain Axis: Resveratrol's Modulation of Key Enzymes in Stress-Related Anxiety.

Stress-related anxiety disorders and anxiety-like behavior in post-traumatic stress disorder (PTSD) are associated with altered neurocircuitry pathways, neurotransmitter systems, and the activities of monoamine and glucocorticoid-metabolizing enzymes. Resveratrol, a natural polyphenol, is recognized for its antioxidant, anti-inflammatory, and antipsychiatric properties. Previous studies suggest that resveratrol reduces anxiety-like behavior in animal PTSD models by downregulating key enzymes such as 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) and monoamine oxidases (MAOs).

Octahedral {TaI} Clusters.

Ta powder reacts with I at 650 °C with the formation of TaI, which belongs to the family of {M(μ-X)} clusters. It undergoes aquation with the formation of the intensely colored [TaI(HO)]. The crystal structure was determined for [TaI(HO)](BPh)·HO (Ta-Ta 2.