Clinical examination of three-dimensional image data of compound anatomical objects, such as complex joints, remains a tedious process, demanding the time and the expertise of physicians. For instance, automation of the segmentation task of the TMJ (temporomandibular joint) has been hindered by its compound three-dimensional shape, multiple overlaid textures, an abundance of surrounding irregularities in the skull, and a virtually omnidirectional range of the jaw's motion-all of which extend the manual annotation process to more than an hour per patient. To address the challenge, we invent a new workflow for the 3D segmentation task: namely, we propose to segment empty spaces between all the tissues surrounding the object-the so-called negative volume segmentation.
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