The Transformative Power of Virtual Hospitals for Revolutionising Healthcare Delivery.

The objective of this narrative review is to explore the advantages and limitations of VHs in delivering healthcare, including access to specialized professionals, streamlined communication, efficient scheduling, integration of electronic health records, ongoing monitoring, and support, transcending geographical boundaries, and resource optimization. Review of literature. The national healthcare systems are facing an alarming rise in pressure due to global shifts.

Enzymatic Activity Profiling Using an Ultrasensitive Array of Chemiluminescent Probes for Bacterial Classification and Characterization.

Identification and characterization of bacterial species in clinical and industrial settings necessitate the use of diverse, labor-intensive, and time-consuming protocols as well as the utilization of expensive and high-maintenance equipment. Furthermore, while cutting-edge identification technologies such as mass spectrometry and PCR are highly effective in identifying bacterial pathogens, they fall short in providing additional information for identifying bacteria not present in the databases upon which these methods rely. In response to these challenges, we present a robust and general approach to bacterial identification based on their unique enzymatic activity profiles.

COVID-19 epidemic peaks distribution in the United-States of America, from epidemiological modeling to public health policies.

COVID-19 prediction models are characterized by uncertainties due to fluctuating parameters, such as changes in infection or recovery rates. While deterministic models often predict epidemic peaks too early, incorporating these fluctuations into the SIR model can provide a more accurate representation of peak timing. Predicting R0, the basic reproduction number, remains a major challenge with significant implications for government policy and strategy.

On the bridge hypothesis in the glass transition of freestanding polymer films.

Freestanding thin polymer films with high molecular weights exhibit an anomalous decrease in the glass-transition temperature with film thickness. Specifically, in such materials, the measured glass-transition temperature evolves in an affine way with the film thickness, with a slope that weakly depends on the molecular weight. De Gennes proposed a sliding mechanism as the hypothetical dominant relaxation process in these systems, where stress kinks could propagate in a reptation-like fashion through so-called bridges, i.

Delayed epidemic peak caused by infection and recovery rate fluctuations.

Forecasting epidemic scenarios has been critical to many decision-makers in imposing various public health interventions. Despite progresses in determining the magnitude and timing of epidemics, epidemic peak time predictions for H1N1 and COVID-19 were inaccurate, with the peaks delayed with respect to predictions. Here, we show that infection and recovery rate fluctuations play a critical role in peak timing.

Interrupting vaccination policies can greatly spread SARS-CoV-2 and enhance mortality from COVID-19 disease: The AstraZeneca case for France and Italy.

Several European countries have suspended the inoculation of the AstraZeneca vaccine out of suspicion that it causes deep vein thrombosis. In this letter, we report some Fermi estimates performed using a stochastic model aimed at making a risk-benefit analysis of the interruption of the delivery of the AstraZeneca vaccine in France and Italy. Our results clearly show that excess deaths due to the interruption of the vaccination campaign injections largely overrun those due to thrombosis even in worst case scenarios of frequency and gravity of the vaccine side effects.

Extreme events for fractional Brownian motion with drift: Theory and numerical validation.

We study the first-passage time, the distribution of the maximum, and the absorption probability of fractional Brownian motion of Hurst parameter H with both a linear and a nonlinear drift. The latter appears naturally when applying nonlinear variable transformations. Via a perturbative expansion in ɛ=H-1/2, we give the first-order corrections to the classical result for Brownian motion analytically.

Cooperative strings and glassy dynamics in various confined geometries.

Previously, we developed a minimal model based on random cooperative strings for the relaxation of supercooled liquids in the bulk and near free interfaces, and we recovered some key experimental observations. In this article, after recalling the main ingredients of the cooperative string model, we study the effective glass transition and surface mobility of various experimentally relevant confined geometries: freestanding films, supported films, spherical particles, and cylindrical particles, with free interfaces and/or passive substrates. Finally, by canceling and restarting any cooperative-chain realization reaching the boundary with a smaller number of steps than the bulk cooperativity, we account for a purely attractive substrate, and explore the impact of the latter in the previous geometries.

Correction: Cooperative strings in glassy nanoparticles.

Correction for 'Cooperative strings in glassy nanoparticles' by Maxence Arutkin et al., Soft Matter, 2017, 13, 141-146.

Cooperative strings in glassy nanoparticles.

Motivated by recent experimental results on glassy polymer nanoparticles, we develop a minimal theoretical framework for the glass transition in spherical confinement. This is accomplished using our cooperative-string model for supercooled dynamics, that was successful at recovering the bulk phenomenology and describing the thin-film anomalies. In particular, we obtain predictions for the mobile-layer thickness as a function of temperature, and for the effective glass-transition temperature as a function of the radius of the spherical nanoparticle - including the existence of a critical particle radius below which vitrification never occurs.