Publications by authors named "Max W S Madureira"
Article Synopsis
- Human T lymphotropic virus 1 (HTLV-1) is linked to inflammatory diseases like HTLV-1-associated myelopathy (HAM), and genetic factors may influence how these diseases develop.
- The study focuses on a specific genetic variation (rs2232365) in the promoter region of the FOXP3 gene, which is important for regulating immune responses and may affect the severity of inflammatory disorders like HAM.
- Researchers analyzed DNA samples from asymptomatic carriers, HAM patients, and controls, finding that certain genotypes were associated with higher proviral loads, CD4 T cell counts, and inflammatory markers in those with HAM.
