Publications by authors named "Max Ole Hubert"

Background And Aims: Chronic liver disease is a growing epidemic, leading to fibrosis and cirrhosis. TGF-β is the pivotal profibrogenic cytokine that activates HSC, yet other molecules can modulate TGF-β signaling during liver fibrosis. Expression of the axon guidance molecules semaphorins (SEMAs), which signal through plexins and neuropilins (NRPs), have been associated with liver fibrosis in HBV-induced chronic hepatitis.

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Article Synopsis
  • The COVID-19 pandemic led to a shift from traditional in-person medical education to e-learning, posing challenges for student motivation and engagement.
  • A team of medical students and physicians created a series of interactive e-learning modules, simulating real patient scenarios within a 10-week curriculum to maintain relevance in clinical education.
  • Student feedback indicated that the case-based, engaging format improved their motivation and allowed them to apply clinical knowledge effectively, suggesting this method can enhance learning even in socially isolated conditions.
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Vascular smooth muscle cells (VSMCs) have been cultured for decades to study the role of these cells in cardiovascular disorders. The most common source of VSMCs is the rat aorta. Here we show the adaptation of this method to isolate and culture mouse aortic VSMCs.

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