Publications by authors named "Max Merilovich"
Longev Healthspan
April 2014
Article Synopsis
- The Mitochondrial Free Radical Theory of Aging (MFRTA) posits that oxidative damage from reactive oxygen species (ROS) in mitochondria contributes to aging and lifespan reduction.
- Recent studies have cast doubt on MFRTA, showing no clear connection between ROS production or neutralization and aging or longevity, despite extensive research across various animal models.
- Emerging evidence suggests that mitochondrial ROS may play a role as intracellular signals in regulating crucial cellular processes, rather than merely causing harmful oxidative damage as initially thought.
