Publications by authors named "Max Krause"

Airborne remote sensing observations were collected at 217 landfills across 17 states in the US in 2023. We used these observations to attribute emissions to major sources, including the landfill work face, where new waste is placed at the landfill and gas-control infrastructure. Methane emissions from the work face appeared to be more prevalent than gas-control infrastructure emissions, with 52 landfills exhibiting work face emissions out of the 115 observed landfills shown to be emitting in 2023.

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Article Synopsis
  • The study investigates how higher temperatures affect the leaching of per- and polyfluoroalkyl substances (PFAS) from municipal solid waste (MSW) landfills, finding that elevated temperatures lead to increased concentrations of PFAS.
  • PFAS leachate from elevated temperature landfills (ETLF) showed significantly higher levels of both PFAS precursors and terminal products compared to normal temperature landfill leachate.
  • The research indicates that the PFAS profiles in landfill leachates differ from those in municipal wastewater, highlighting the complexity and variability of PFAS sources, necessitating further investigation to understand their impacts on waste treatment systems.
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As part of its commitment to the United Nations Framework Convention on Climate Change, the U.S. annually develops a national estimate of methane emissions from municipal solid waste (MSW) landfills by aggregating activity data from each facility.

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Article Synopsis
  • Deep brain stimulation (STN-DBS) is a treatment for people with advanced Parkinson's disease that helps with movement problems, but results can be different for each person.
  • Researchers studied the brain scans of 49 Parkinson's patients to see if certain brain measurements could predict how well they would do in areas not just related to movement after treatment.
  • They found that while losing brain volume in some areas like the frontal cortex linked to worse motor outcomes, it didn't really help predict non-motor issues, meaning it might not be super helpful for choosing which patients should get the treatment.
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Methane emissions from solid waste may represent a substantial fraction of the global anthropogenic budget, but few comprehensive studies exist to assess inventory assumptions. We quantified emissions at hundreds of large landfills across 18 states in the United States between 2016 and 2022 using airborne imaging spectrometers. Spanning 20% of open United States landfills, this represents the most systematic measurement-based study of methane point sources of the waste sector.

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The leachate collection system (LCS) and leak detection system (LDS) flow rate data from 240 cells (or a combination of cells) at 54 municipal solid-waste landfills (located in seven US states) with double-liner systems were analyzed to assess the performance of the primary liner system. The average LCS leachate collection rates for the study sites ranged from 380 L ha day (40.7 gal.

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Elevated temperature landfills (ETLFs) are municipal solid waste (MSW) landfills that have been impacted by subsurface exothermic reactions (SERs) and display unusual gas and leachate composition. Leachate quantity and quality data were analyzed to identify indicators of a SER at an ETLF in Ohio, USA. ETLF leachate generation increased from 2.

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Landfills manage materials containing per- and polyfluoroalkyl substances (PFAS) from municipal solid waste (MSW) and other waste streams. This manuscript summarizes state and federal initiatives and critically reviews peer-reviewed literature to define best practices for managing these wastes and identify data gaps to guide future research. The objective is to inform stakeholders about waste-derived PFAS disposed of in landfills, PFAS emissions, and the potential for related environmental impacts.

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Liquid addition to landfilled municipal solid waste (MSW) is a practice employed to accelerate the biodegradation of the organic fraction of MSW and ensuing gas generation. Pore landfill gas (LFG) and leachate pressure from the added moisture and enhanced gas generation are expected to impact the geotechnical stability of landfill slopes. The impact of moisture addition and gas collection on the stability of landfills was numerically modeled using transient isothermal dual-phase flow and slope stability modeling.

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The early stages of municipal solid waste degradation in landfills are complex harmonies of physical, biological, and chemical interactions that all work in concert to degrade trash into smaller and more stable materials. While many approaches have been taken to understand parts of this process, this new work attempted to simulate the early stages of landfills in controlled laboratory environments while observing the impacts of food waste content at different concentrations. This was completed by operating landfill lysimeters in a laboratory for approximately 1000 days, simulating landfill interior conditions while measuring the gas and liquid byproducts to study the impact of food waste presence in these environments.

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Landfill gas (LFG) wellhead data were compared to understand the range of observations due to unique conditions at five elevated temperature landfills (ETLFs) in the U.S. Correlations of the primary gas ratio, CH:CO, show distinct compositional indicators for (1) typical operation, (2) subsurface exothermic reactions (SERs), (3) high moisture content, and (4) air intrusion that can help operators and regulators diagnose conditions across gas extraction wells.

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This data brief presents leachate disposal and management data for 43 active or closed municipal solid waste (MSW) landfills and planar surface areas for 40 of those landfills in Ohio, USA. Data were extracted from publicly available Annual Operational Reports from the Ohio Environmental Protection Agency (Ohio EPA) and consolidated into a digital dataset of two delimited text files. A total of 9,985 data points represent monthly leachate disposal totals, arranged by management type and by landfill.

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Remote locations, small communities, and weather prohibit the operation of piped sanitary sewers in many Alaska Native Villages (ANVs). Research was conducted to understand the technical feasibility of installing anaerobic digesters (ADs) in remote ANVs which would be heated by solar thermal collectors. Biochemical methane potential (BMP) assays were conducted to understand the effect of freezing and thawing on methanogenic activity of synthetic human feces.

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Aims: Pulmonary arterial hypertension (PAH) is a devastating disease with limited therapeutic options. Vascular remodelling of pulmonary arteries, characterized by increased proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs), is a hallmark of PAH. Here, we aimed to systematically characterize coagulation-independent effects of key coagulation proteases thrombin and Factor Xa (FXa) and their designated receptors, protease-activated receptor (PAR)-1 and -2, on PASMCs in vitro and experimental PAH in vivo.

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The release of persistent per- and polyfluoroalkyl substances (PFAS) into the environment is a major concern for the United States Environmental Protection Agency (U.S. EPA).

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Concentrations of per- and poly-fluoroalkyl substances (PFAS) present in wastewater treatment biosolids are a growing concern. Pyrolysis is a thermal treatment technology for biosolids that can produce a useful biochar product with reduced levels of PFAS and other contaminants. In August 2020, a limited-scope study investigated target PFAS removal of a commercial pyrolysis system processing biosolid with the analysis of 41 target PFAS compounds in biosolids and biochar performed by two independent laboratories.

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Water above 374 °C and 22.1 MPa, becomes supercritical, a special state where organic solubility increases and oxidation processes are accelerated. Supercritical water oxidation (SCWO) has been previously shown to destroy hazardous substances such as halogenated compounds.

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Enhanced signaling via RTKs in pulmonary hypertension (PH) impedes current treatment options because it perpetuates proliferation and apoptosis resistance of pulmonary arterial smooth muscle cells (PASMCs). Here, we demonstrated hyperphosphorylation of multiple RTKs in diseased human vessels and increased activation of their common downstream effector phosphatidylinositol 3'-kinase (PI3K), which thus emerged as an attractive therapeutic target. Systematic characterization of class IA catalytic PI3K isoforms identified p110α as the key regulator of pathogenic signaling pathways and PASMC responses (proliferation, migration, survival) downstream of multiple RTKs.

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A critical examination of the US Environmental Protection Agency's (US EPA's) Greenhouse Gas Reporting Program (GHGRP) database provided an opportunity for the largest evaluation to date of landfilled waste decomposition kinetics with respect to different US climate regimes. In this paper, 5-8 years of annual methane collection data from 114 closed landfills located in 29 states were used to estimate site-specific waste decay rates (k) and methane collection potentials (Lc). These sites account for approximately 9% of all landfills required to report GHG emissions to the US EPA annually.

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Deep brain stimulation of the subthalamic nucleus is an effective and established therapy for patients with advanced Parkinson's disease improving quality of life, motor symptoms and non-motor symptoms. However, there is a considerable degree of interindividual variability for these outcomes, likely due to variability in electrode placement and stimulation settings. Here, we present probabilistic mapping data from a prospective, open-label, multicentre, international study to investigate the influence of the location of subthalamic nucleus deep brain stimulation on non-motor symptoms in patients with Parkinson's disease.

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The Intergovernmental Panel on Climate Change (IPCC) protocol for predicting national methane emission inventories from landfills was published 22 years ago in the 1996 Revised Guidelines. There currently exists a broad dataset to review landfill parameters and reported values and their appropriateness in use and application in a range of site-specific, regional, and national estimates. Degradable organic carbon (DOC) content was found to range from 0.

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Methane generation potential, L, is a primary parameter of the first-order decay (FOD) model used for prediction and regulation of landfill gas (LFG) generation in municipal solid waste (MSW) landfills. The current US EPA AP-42 default value for L, which has been in place for almost 20 years, is 100 m CH/Mg MSW as-discarded. Recent research suggests the yield of landfilled waste could be less than 60 m CH/Mg MSW.

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The effects of temperature and substrate size on the biochemical methane potential (BMP) assay were tested using eight municipal solid waste components. Two sample sizes were tested; size-reduced particles (x < 2 mm) which are typically used for BMP assays and unground samples (x > 20-100 mm) more similar to an as-disposed condition. Two incubation temperatures (35 and 55 °C) were tested for each component.

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Unlabelled: Landfill gas (LFG) generation is predicted by a first-order decay (FOD) equation that incorporates two parameters: a methane generation potential (L) and a methane generation rate (k). Because non-hazardous waste landfills may accept many types of waste streams, multiphase models have been developed in an attempt to more accurately predict methane generation from heterogeneous waste streams. The ability of a single-phase FOD model to predict methane generation using weighted-average methane generation parameters and tonnages translated from multiphase models was assessed in two exercises.

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Recently, gypsum drywall products imported to the United States (US) were found to cause metal corrosion and tarnishing in some homes, often necessitating that this drywall be discarded. Research assessed the potential implications of recycling and landfilling corrosive/imported drywall. Samples of corrosive drywall were collected from homes in Florida, US and these characteristics were assessed relative to domestically-produced drywall purchased from retail outlets.

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