Sublesional fat grafting leads to a temporary improvement of wound healing in chronic leg ulcers: A prospective, randomised clinical trial.

Chronic wounds remain a therapeutic and financial challenge for physicians and the health care systems. Innovative, inexpensive and effective treatment methods would be of immense value. The sublesional fat grafting could be such treatment, although effectiveness and safety have only been assessed in a few randomised clinical trials.

Preoperative Perforator Mapping in DIEP Flaps for Breast Reconstruction. The Impact of New Contrast-Enhanced Ultrasound Techniques.

Deep inferior epigastric artery flaps (DIEP) represent the gold standard of autologous breast reconstruction. Due to significant variations in vascular anatomy, preoperative perforator mapping (PM) is mandatory in order to ensure the presence of a sufficient perforator within the flap. In this regard, CT angiography (CTA) is currently the method of choice.

A paradigm shift in orthognathic surgery? A comparison of navigation, computer-aided designed/computer-aided manufactured splints, and "classic" intermaxillary splints to surgical transfer of virtual orthognathic planning.

Purpose: Advances in computers and imaging have permitted the adoption of 3-dimensional (3D) virtual planning protocols in orthognathic surgery, which may allow a paradigm shift when the virtual planning can be transferred properly. The purpose of this investigation was to compare the versatility and precision of innovative computer-aided designed and computer-aided manufactured (CAD/CAM) surgical splints, intraoperative navigation, and "classic" intermaxillary occlusal splints for surgical transfer of virtual orthognathic planning.

Material And Methods: The protocols consisted of maxillofacial imaging, diagnosis, virtual orthognathic planning, and surgical planning transfer using newly designed CAD/CAM splints (approach A), navigation (approach B), and intermaxillary occlusal splints (approach C).

Computer-assisted orthognathic surgery: waferless maxillary positioning, versatility, and accuracy of an image-guided visualisation display.

There may well be a shift towards 3-dimensional orthognathic surgery when virtual surgical planning can be applied clinically. We present a computer-assisted protocol that uses surgical navigation supplemented by an interactive image-guided visualisation display (IGVD) to transfer virtual maxillary planning precisely. The aim of this study was to analyse its accuracy and versatility in vivo.

A comparative study of two different techniques for complete bilateral cleft lip repair using two-dimensional photographic analysis.

Background: The aim of this study was to compare the clinical outcomes of two techniques to repair complete bilateral cleft lip by using indirect two-dimensional photographic analysis.

Methods: One hundred eight bilateral cleft patients were included in this study, 54 patients operated on with the Millard technique and 54 patients operated on with the Afroze technique. Each group of patients was further separated into two subgroups containing symmetrical and asymmetrical cleft lips.

Adipose-derived stem cells and keratinocytes in a chronic wound cell culture model: the role of hydroxyectoine.

Chronic wounds represent a major socio-economic problem in developed countries today. Wound healing is a complex biological process. It requires a well-orchestrated interaction of mediators, resident cells and infiltrating cells.

Comparison of different autografts for aural cartilage in aesthetic rhinoplasty: is the tragal cartilage graft a viable alternative?

Auricular cartilage is an important source of grafts for various reconstructive procedures such as aesthetic rhinoplasty. The purpose of this investigation was to compare tragal cartilage with auricular cartilage harvested from the concha and scapha, and describe its clinical viability, indications, and morbidity in rhinoplasty. A total of 150 augmentation rhinoplasties with a total of 170 grafts were included.

The predictors of implant failure after maxillary sinus floor augmentation and reconstruction: a retrospective study of 1045 consecutive implants.

Objective: To assess the predictors of implant failure after grafted maxillary sinus (GMS).

Material And Methods: A total of 1045 implants were inserted in 224 patients/347 GMS during a period of 14 years. Kaplan-Meyer and multivariate log-regression analysis were used to assess the following variates: patient's age, gender, smoker/nonsmoker, American Society of Anesthesiologists (ASA) class, one/two-stage surgery, merged/submerged healing, membrane, antibiotics, auto/allo/xenogenic bone grafts, implant's lengths/surface/diameter, crestal bone atrophy/quality, implant region, prosthetics, opposing dentition, and implant proximity to evaluate the predictors and relative risk (hazard ratio [HR]) of implant failure.

Early single-shot intravenous steroids do not affect pulmonary complications and mortality in burned or scalded patients.

Background And Objectives: Inhalation injury, especially in combination with cutaneous burns, is the major cause of morbidity and mortality in patients admitted to burn care centers. Either with or without the presence of a cutaneous burn, inhalation injury contributes to high risk for developing severe pulmonary complications. Steroids may reduce a prolonged and destructive inflammatory response to toxic or allergic substances.

Evaluation of the course of the inferior alveolar nerve in the mental foramen by cone beam computed tomography.

Purpose: Implant placement in the edentulous anterior mandible is frequently performed to stabilize prosthetic superstructures. The position of the inferior alveolar nerve (IAN), especially in an atrophic mandible, has to be considered to position implants properly. In this study, the prevalence of looping of the IAN was retrospectively determined to assess the need for imaging prior to implant placement in the anterior mandible.

CBCT device dependency on the transfer accuracy from computer-aided implantology procedures.

Objectives: To evaluate the potential influence of different cone-beam computed tomography (CBCT) devices on the transfer accuracy of an open-source system for computer-aided implantology (CAI).

Material And Methods: A total of 108 implants in 18 partially edentulous patient-equivalent models were planned and fully guided implants were inserted using an open-source CAI system with three different CBCT devices. After follow-up CBCT and fiducial marker-matching procedure, linear horizontal, vertical, and maximal three-dimensional deviations, as well as angle deviations between the virtual planning data and the surgical results were calculated.

Computer-assisted orthognathic surgery: feasibility study using multiple CAD/CAM surgical splints.

Objective: We present a virtual planning protocol incorporating a patented 3-surgical splint technique for orthognathic surgery. The purpose of this investigation was to demonstrate the feasibility and validity of the method in vivo.

Materials And Methods: The protocol consisted of (1) computed tomography (CT) or cone-beam computed tomography (CBCT) maxillofacial imaging, optical scan of articulated dental study models, segmentation, and fusion; (2) diagnosis and virtual treatment planning; (3) computed-assisted design and manufacture (CAD/CAM) of the surgical splints; and (4) intraoperative surgical transfer.

Prevalence of pathologic findings in the maxillary sinus in cone-beam computerized tomography.

Objective: The aim of this study was to assess the prevalence of pathologic findings in the maxillary sinus by using cone-beam computerized tomography (CBCT).

Study Design: One thousand twenty-nine consecutive CBCT scans were retrospectively inspected for pathologic findings in the maxillary sinus by 3 observers. Findings were differentiated by mucosal thickening, partial opacification with liquid accumulation, total opacification, and polypoidal mucosal thickening.

Donor-site morbidity of ear cartilage autografts.

Background: The external ear provides a versatile cartilage source for reconstructive procedures, especially for augmentative rhinoplasty. The authors evaluated the short- and long-term morbidity associated with ear cartilage harvest using concha, tragus, and scapha as donor sites.

Methods: The study included 52 patients in whom a cartilage graft from the external ear was harvested between February of 2001 and June of 2005.

Application of an augmented reality tool for maxillary positioning in orthognathic surgery - a feasibility study.

Background: An augmented reality tool for computer assisted surgery named X-Scope allows visual tracking of real anatomical structures in superposition with volume rendered CT or MRI scans and thus can be used for navigated translocation of bony segments.

Methods: In a feasibility study X-Scope was used in orthognathic surgery to control the translocation of the maxilla after Le Fort I osteotomy within a bimaxillary procedure. The situation achieved was compared with the pre-operative situation by means of cephalometric analysis on lateral and frontal cephalograms.