Mandibular sagittal split osteotomy: is a bicortical 2-screw osteosynthesis adequate?

The aim of this study was to prospectively evaluate the accuracy and reliability of the use of the Hunsuck/Epker–type mandibular split osteotomy together with osteosynthesis with placement of 2 bicortical positioning screws without the adjunctive use of a postoperative maxilla-mandibular fixation in the treatment of mandibular dentofacial deformities. We analyzed the clinical and radiologic data of 54 patients with dentofacial deformities. We recorded age and sex, status of healing, and complications.

Large-scale production of bioactive ingredients as supplements for healthy human and animal nutrition.

In this review, synthetic strategies and the development of environmentally benign methods for the production of economically important vitamins, carotenoids, and nutraceuticals used as food and feed supplements are illustrated by selected examples. The application of efficient catalytic transformations in multi-step chemical syntheses of such natural products enables technically feasible and cost-effective processes. For the preparation of fat-soluble (isoprenoid) vitamins A and E and the water-soluble vitamin (+)-biotin, homogeneous metal catalysis, including enantioselective transformations, heterogeneous and enzymatic catalysis serve as key methodologies.

Severe dental malocclusion: a rare and insidious complication of mandibular advancement devices for obstructive sleep apnea syndrome treatment.

Objectives: Severe dental malocclusion resulting from mandibular advancement devices (MADs) for obstructive sleep apnea syndrome (OSAS) is extremely rare. Reporting of such situations is therefore useful for clinicians managing OSAS.

Study Design: We report the unusual cases of 4 patients who developed a severe circular dental open bite related to the use of a MAD.