Publications by authors named "Max Grogan"
Article Synopsis
- Proprioception, a sense crucial for movement control, remains underexplored, particularly in how limb position is mapped in the brain's somatosensory cortex.
- The researchers developed a topographic variational autoencoder (topo-VAE) that, while not based on actual neural data, successfully mimics key aspects of proprioception observed in monkey movement studies.
- Their model predicts a specific geometry for how neurons encode movement across the cortex and suggests that few neurons focus on single joints, offering insights into sensory feedback applications in brain-computer interfaces and robotics.
Percutaneous osseointegrated (OI) prostheses (POPs) are used to skeletally attach artificial limbs in amputees. While any permanent percutaneous interface is at risk of becoming infected by the resident microbiota colonizing the stoma, most of these patients remain infection-free. Avoidance of infection likely depends upon a mechanically and/or biologically stable skin-to-implant interface.
View Article and Find Full Text PDFSkin is colonized by microbial communities (microbiota) that participate in immune homeostasis, development and maintenance of barrier function, and protection from pathogens. The past decade has been marked by an increased interest in the skin microbiota and its role in cutaneous health and disease, in part due to advances in next-generation sequencing platforms that enable high-throughput, culture-independent detection of bacteria, fungi, and viruses. Various approaches, including bacterial 16S ribosomal RNA gene sequencing and metagenomic shotgun sequencing, have been applied to profile microbial communities colonizing healthy skin and diseased skin including atopic dermatitis, psoriasis, and acne, among others.
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