[Traumatic optic pit-Optic nerve evulsion caused by indirect ocular trauma].

This article describes the case of a 28-year-old man who suffered an optic nerve evulsion (ONE) after falling from a height of 5 m. On admission visual acuity in the affected left eye was light perception, direct pupillary reaction was unresponsive, and the eye was hypotonic. Because of deep eyelid laceration, hyphemia and severe vitreous hemorrhage a globe rupture was suspected and a surgical exploration with vitrectomy was performed.

[Bilateral periocular necrotizing fasciitis with unilateral orbital involvement].

The case of an 82-year-old woman with bilateral necrotizing fasciitis and unilateral orbital involvement is presented. A mixed infection consisting of Streptococcus pyogenes, Staphylococcus aureus, and Aspergillus fumigatus could be verified. The latter was detected by molecular pathological investigations.

Hydrogen peroxide modulates energy metabolism and oxidative stress in cultures of permanent human Müller cells MIO-M1.

In this study the influence of hydrogen peroxide (H O ) on the redox state, NADH protein binding, and mitochondrial membrane potential in Müller cells is investigated. Cultures of permanent human Müller cells MIO-M1 were exposed to H O in 75 µM and 150 µM concentration for two hours. Fluorescence emission spectra and lifetimes were measured by two-photon microscopy (excitation wavelength: 740 nm) at the mitochondria which were identified in the microscopic images by their fluorescence properties (spectra and intensity).